Е.А. Burakovа, K. Klabenkova, A. Derzhalova, D. E. Patrushev, S. N. Bizyaev, А.А. Fokinа
{"title":"新Р-modified寡核苷酸作为下一代反义药物","authors":"Е.А. Burakovа, K. Klabenkova, A. Derzhalova, D. E. Patrushev, S. N. Bizyaev, А.А. Fokinа","doi":"10.37747/2312-640x-2021-19-56-59","DOIUrl":null,"url":null,"abstract":"Replacement of phosphate groups in internucleotidic positions by such linkages as phosphorylimines or sulfonyl phosphoramidates results in the formation of a wide spectrum of new DNA and RNA analogues that demonstrate properties corresponding to the next generation antisense therapeutics.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"43 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"NEW Р-MODIFIED OLIGONUCLEOTIDES AS NEXT GENERATION ANTISENSE AGENTS\",\"authors\":\"Е.А. Burakovа, K. Klabenkova, A. Derzhalova, D. E. Patrushev, S. N. Bizyaev, А.А. Fokinа\",\"doi\":\"10.37747/2312-640x-2021-19-56-59\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Replacement of phosphate groups in internucleotidic positions by such linkages as phosphorylimines or sulfonyl phosphoramidates results in the formation of a wide spectrum of new DNA and RNA analogues that demonstrate properties corresponding to the next generation antisense therapeutics.\",\"PeriodicalId\":13077,\"journal\":{\"name\":\"http://eng.biomos.ru/conference/articles.htm\",\"volume\":\"43 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"http://eng.biomos.ru/conference/articles.htm\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.37747/2312-640x-2021-19-56-59\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"http://eng.biomos.ru/conference/articles.htm","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37747/2312-640x-2021-19-56-59","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
NEW Р-MODIFIED OLIGONUCLEOTIDES AS NEXT GENERATION ANTISENSE AGENTS
Replacement of phosphate groups in internucleotidic positions by such linkages as phosphorylimines or sulfonyl phosphoramidates results in the formation of a wide spectrum of new DNA and RNA analogues that demonstrate properties corresponding to the next generation antisense therapeutics.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
