用于光学神经接口的植入式装置

T. Abaya, M. Diwekar, S. Blair, P. Tathireddy, L. Rieth, F. Solzbacher
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引用次数: 0

摘要

光神经控制需要依赖于实验目标和生物模型的光传递技术。几个光源和神经接口已经实现,具有以下一个或多个标准:深度照明,特定和/或全面访问,光谱控制,时间精度,高分辨率模式。我们开发了3D针状波导阵列,作为潜在的紧凑神经接口,可将90%的输入光传输到组织中>1mm的深度;由于阵列可以在定义的深度、波长和模式下进行修改以投射不同的照明体积,因此可以很容易地适应各种实验范例。
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Implantable devices for optical neural interfaces
Optical neural control requires light delivery techniques dependent on the experimental goal and biological model. Several light sources and neural interfaces have been implemented featuring one or more of the following criteria: deep illumination, specific and/or comprehensive access, spectral control, temporal precision, high resolution patterning. We've developed 3D needle-type waveguide arrays as potentially compact neural interfaces for light transmission of as much as 90% of input light to depths >1mm in tissue; various experimental paradigms are easily accommodated as the arrays can be modified to project different illumination volumes at defined depths, wavelengths and patterns.
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