干眼病诊断与治疗的最新进展

M. Venkatesh
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摘要

干眼病(DED)是一种眼表疾病,由于高渗透压和泪液分泌不足而导致眼睛湿润,导致润滑减少和眼表炎症,导致视力障碍和眼睛不适。长时间使用电脑、笔记本电脑和手机会导致眨眼次数减少,使眼睛的黏液层变薄,导致泪膜不稳定和DED。全世界有数千万人受到DED的影响。它也被称为干燥综合征,影响眼睛的泪腺,减少泪液分泌,导致眼内泪液膜的形成和睑板腺功能障碍。在这里,我们讨论了用于识别DED的各种诊断方法以及用于诊断DED的新兴技术。治疗方案根据疾病的严重程度进行讨论,包括新的治疗方法,如自体血清、局部皮质类固醇和抗炎药。
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Current advances in dry eye disease diagnosis and treatment
Dry eye disease (DED) is a disorder of the ocular surface caused due to hyperosmolarity and insufficient production of tears to moisturize the eye, which leads to less lubrication and ocular surface inflammation and results in visual disturbance and discomfort to the eye. Long-time use of computers, laptops, and mobiles causes less blinking, making the eye's mucin layer thinner, leading to tear-film instability and DED. Tens of millions of people are getting affected by DED worldwide. It is also known as Sjogren's syndrome, which impacts the lacrimal gland of the eyes, decreases tear secretion, and causes the development of aqueous tear film in the eyes and meibomian gland dysfunction. Here we have discussed the various diagnosis methods used for identifying DED and also the emerging technologies for the diagnosis of DED. The treatment options are discussed as per the disease's severity, including novel therapies like autologous serum, topical corticosteroids, and anti-inflammatory agents.
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