慢性风疹性痛风关节炎伴巨足部感染1例

Wayan Subawa, P. Astawa, Nico Lie, Claudia Santosa Richard Af
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摘要

痛风性关节炎是一种嘌呤代谢紊乱,导致高尿酸血症和尿酸钠一水晶体沉积在肌肉骨骼系统和其他。陶土沉积物是众所周知的导致关节破坏,这可能是复杂的继发感染条件。痛风的患病率和发病率从< 1%到< 6.8%不等,发病率从0.58 / 1000人/年到2.89 / 1000人/年不等。我们报告一例56岁男性患者,自9岁以来,他的双脚踝和脚都有肿块。从体格检查中,我们发现他的脚上有多个石斑病,右脚有感染的巨足,并伴有继发感染。实验室结果和影像学证实慢性痛风性关节炎,增强了这种症状。对于临床医生来说,诊断痛风关节炎有时相当具有挑战性,需要通过关节或痛风热望进行调查。还有一些其他的诊断经常模仿痛风关节炎的临床特征,如蜂窝织炎,瑞特病,假性痛风和类风湿性关节炎(RA)。痛风性关节炎本身通常采用保守治疗,但10%的临床痛风患者发展为破坏性痛风石。这种阶段需要进一步的手术干预,包括;手术重建、清创、切除、关节置换术、关节融合术甚至截肢。
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Chronic tophaceous gout arthritis with infected giant podagra on first ray: a case report
Gout Arhritis is a purine metabolism disorder that leads to hyperuricemia and monosodium urate monohydrate crystal deposition in musculoskeletal system and others. Tophaceous deposits are well-known to lead joint destruction, which can be complicated by secondary infection condition. The prevalence and incidence of gout vary from a prevalence of < 1% to < 6.8% and an incidence of 0.58 per 1,000 person/years to 2.89 per 1,000 person/years. We presented a case of 56-years-old male came with the complained of lumps on both ankles and feet since 9 y. From physical examination, we found multiple tophi on his feet and infected giant podagra on the right foot associated with secondary infection. This symptoms is enhanced by laboratory result and imaging that confirming chronic gout arthritis. For clinician, diagnosing gout arthritis sometimes quite challenging which requiring investigation through joint or tophi aspirations. There are some other diagnosis that often mimicking the clinical feature of gout arthritis like, cellulitis, Reiter's disease, Pseudogout and Rheumatoid Arthritis (RA). Gout arthritis itself commonly treated with conservative treatment but 10% of patients with clinical gout developed destructive tophi. This kind of stage will need further surgical intervention, including; surgical reconstruction debridement and resection arthroplasty, joint fusion and even amputation.
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