利希海姆病:恶性贫血的一种罕见表现

S. Shimpiger, S. J. Nishigandha, R. Richa, U. Sushma
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引用次数: 0

摘要

脊髓亚急性合并变性(SACD)是维生素B12缺乏的重要神经系统并发症。它是一种重要的可治疗的进行性神经功能障碍的原因。我们报告一例12岁女孩,其表现为脊髓SACD的特征,维生素B12水平低,抗壁细胞抗体阳性,提示自身免疫性病因所致的维生素B12缺乏。这名女孩开始接受肌肉注射维生素B12治疗。之后她的神经系统完全恢复了。由于自身免疫性病因,建议终生补充肠外维生素B12。
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Lichtheim disease: A rare manifestation of pernicious anemia
Subacute combined degeneration of the spinal cord (SACD) is an important neurological complication of vitamin B12 deficiency. It is an important treatable cause of progressive neurological disability. We report a case of a 12-year-old girl, which presented with features of SACD of the spinal cord with low vitamin B12 levels and positive anti-parietal cell antibodies, suggesting vitamin B12 deficiency due to autoimmune etiology. The girl was started on a regimen of intramuscular vitamin B12 treatment. After which she had complete neurological recovery. She was advised of lifelong supplementation of parenteral vitamin B12 due to the autoimmune etiology.
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