Guillain - Barre syndrome as the first presentation in a patient with systemic lupus erythromatous; case report

Systemic Lupus Erythromatous (SLE) is an auto immune disease characterized by multi-organ affection, Guillain–Barre syndrome (GBS) is considered as an unusual and one of the least neuropsychiatric syndromes in SLE, this case report aiming to report a rare association of GBS as an initial presentation for an SLE in a female patient. A middle age female was presented with palpitation, shortness of breath and body weakness, she was admitted for four days and diagnosed with atypical GBS. She received Intravenous immunoglobulin (IVIG) for three days but no improvement was been noticed. The patient complained of dry cough, shortness of breath, palpitations and generalized weakness in association with back pain and paraesthesia of the fingers. General examination and lab workup were done and revealed a presence of SLE in relation to GBS. IVIG was then commenced 0.4 g/kg body/weight/day with Hydroxychloroquine 200mg tabs BID, Prednisolone 40mg, calcicare and Mycophenolatemofetil. Significant improvement was noted after receiving the above-mentioned medications and over a period of three months all her symptoms and complains were subside.