三维稳定流动中的二次流和壁面剪切应力

E. Finol, C. Amon
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引用次数: 6

摘要

腹主动脉瘤(AAAs)是一种球囊状的扩张,常见于腹主动脉肾下段,位于肾动脉和髂分叉之间。AAA患者的平均年龄为67岁,男性多于女性,比例为4:1。腹主动脉瘤破裂是美国第13大死因,50岁以上人群中每250人中就有1人受其影响。AAAs通常没有症状,在几年甚至几十年的时间里慢慢扩大。已知影响动脉瘤破裂风险的因素有:动脉瘤的最大横向尺寸、扩张速度、相对于患者体型的相对大小、吸烟和患者的家族史。5年生存率仅为19%,破裂后的总死亡率可超过90%[1]。因此,动脉瘤筛查和确定可能在动脉瘤生长和破裂中起重要作用的因素已成为研究这一临床问题的重要因素。
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Secondary Flow and Wall Shear Stress in Three-Dimensional Steady Flow AAA Hemodynamics
Abdominal Aortic Aneurysms (AAAs) are balloon-shaped expansions commonly found in the infrarenal segment of the abdominal aorta, between the renal arteries and the iliac bifurcation. The mean age of patients with AAA is 67 years and males are affected more often than women in a ratio of 4:1. Abdominal aortic aneurysm rupture is the 13th leading cause of death in the United States, affecting 1 in 250 individuals greater than 50 years of age. AAAs usually remain asymptomatic while slowly enlarging over a period of years or even decades. Factors that are known to affect the risk of aneurysm rupture are: maximum transverse dimension of the aneurysm, its expansion rate, its relative size compared to the patient’s body size, smoking, and family history of the patient. The five-year survival rate is only 19% and the overall mortality rate following rupture may exceed 90% [1]. Therefore, aneurysm screening and determination of the factors that may have an important role in aneurysm growth and rupture have become important elements in the investigation of this clinical problem.
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