{"title":"抗炎药β-甘草次酸的阴离子甜味衍生物","authors":"T. Toyoshima, S. Tamagaki","doi":"10.5650/JOS1996.49.1407","DOIUrl":null,"url":null,"abstract":"Anionic derivatives of β-glycyrrhetinic acid (GA) were prepared and assessed for sweetness. It was found that the presence of both a carboxyl group (COOH, free form) at C20 position and a carboxylate moiety (COO-) at C3 position in the GA molecule is essential for sweet taste. A plausible mechanism for sweet taste is proposed.","PeriodicalId":16191,"journal":{"name":"Journal of Japan Oil Chemists Society","volume":"6 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2000-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Anionic Sweet Tasting Derivatives of the Anti-Inflammatory Drug β-Glycyrrhetinic Acid\",\"authors\":\"T. Toyoshima, S. Tamagaki\",\"doi\":\"10.5650/JOS1996.49.1407\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Anionic derivatives of β-glycyrrhetinic acid (GA) were prepared and assessed for sweetness. It was found that the presence of both a carboxyl group (COOH, free form) at C20 position and a carboxylate moiety (COO-) at C3 position in the GA molecule is essential for sweet taste. A plausible mechanism for sweet taste is proposed.\",\"PeriodicalId\":16191,\"journal\":{\"name\":\"Journal of Japan Oil Chemists Society\",\"volume\":\"6 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2000-11-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Japan Oil Chemists Society\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5650/JOS1996.49.1407\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Japan Oil Chemists Society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5650/JOS1996.49.1407","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Anionic Sweet Tasting Derivatives of the Anti-Inflammatory Drug β-Glycyrrhetinic Acid
Anionic derivatives of β-glycyrrhetinic acid (GA) were prepared and assessed for sweetness. It was found that the presence of both a carboxyl group (COOH, free form) at C20 position and a carboxylate moiety (COO-) at C3 position in the GA molecule is essential for sweet taste. A plausible mechanism for sweet taste is proposed.
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