{"title":"壳聚糖包被磷酸钙颗粒作为眼部组织药物递送载体","authors":"","doi":"10.37747/2312-640x-2021-19-88-90","DOIUrl":null,"url":null,"abstract":"Chitosan-covered calcium phosphate particles are promising carriers for the delivery of low-molecular-weight drugs to ocular tissues. The inclusion of the angiotensin-converting enzyme inhibitor enalaprilat into these particles increases the retention time of the drug in the tear, enhances the effectiveness of intraocular pressure decrease, and prolongs the drug action.","PeriodicalId":13077,"journal":{"name":"http://eng.biomos.ru/conference/articles.htm","volume":"41 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"CHITOSAN-COATED CALCIUM PHOSPHATE PARTICLES AS CARRIERS FOR DRUG DELIVERY TO OCULAR TISSUES\",\"authors\":\"\",\"doi\":\"10.37747/2312-640x-2021-19-88-90\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Chitosan-covered calcium phosphate particles are promising carriers for the delivery of low-molecular-weight drugs to ocular tissues. The inclusion of the angiotensin-converting enzyme inhibitor enalaprilat into these particles increases the retention time of the drug in the tear, enhances the effectiveness of intraocular pressure decrease, and prolongs the drug action.\",\"PeriodicalId\":13077,\"journal\":{\"name\":\"http://eng.biomos.ru/conference/articles.htm\",\"volume\":\"41 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"http://eng.biomos.ru/conference/articles.htm\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.37747/2312-640x-2021-19-88-90\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"http://eng.biomos.ru/conference/articles.htm","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37747/2312-640x-2021-19-88-90","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
CHITOSAN-COATED CALCIUM PHOSPHATE PARTICLES AS CARRIERS FOR DRUG DELIVERY TO OCULAR TISSUES
Chitosan-covered calcium phosphate particles are promising carriers for the delivery of low-molecular-weight drugs to ocular tissues. The inclusion of the angiotensin-converting enzyme inhibitor enalaprilat into these particles increases the retention time of the drug in the tear, enhances the effectiveness of intraocular pressure decrease, and prolongs the drug action.