组织工程用碱活化表面Ti6Al4V支架

2021 IEEE 11th International Conference Nanomaterials: Applications & Properties (NAP) Pub Date : 2021-09-05 DOI:10.1109/NAP51885.2021.9568619

Y. Husak, Kateryna Zaitseva, A. Turlybekuly, K. Diedkova, M. Sliusarenko, Illya Yanko, S. Kyrylenko, A. Pogrebnjak, W. Simka, M. Pogorielov

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引用次数: 0

摘要

骨科植入物的骨相容性可以通过表面生物活化和提供仿生结构来增强。为了满足骨组织承载功能的要求，采用选择性激光熔化(SLM)技术制备了拓扑结构改进的支架材料。为实现这些目标，从宏观和微观两个层面进行了考虑。种植体表面的矿化改善了细胞的附着和扩散。用氢氧化钠处理Ti6Al4V植入体后，钛酸盐表面层具有良好的纳米结构。附加的表面处理可用于改善slm制备的多孔支架的生物学性能。

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Ti6Al4V Scaffolds with Alkali Activated Surfaces for Tissue Engineering

Osteocompatibility of orthopedic implants can be enhanced by surface bioactivation and by providing biomimetic architecture. Selective laser melting (SLM) is used to produce scaffold materials with ameliorated topology to meet the requirements of the load-bearing function of a bone tissue. Both macro- and micro levels were considered to achieve these goals. Mineralization of the implant surfaces improves cell attachment and spreading. Treatment of Ti6Al4V implant with sodium hydroxide resulted in a titanate surface layer with well-developed nanostructure. Additional surface treatment can be used to improve the biological properties of the SLM-fabricated porous scaffolds.

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2021 IEEE 11th International Conference Nanomaterials: Applications & Properties (NAP)

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