全静脉麻醉促进神经肌肉监测的脑桥角肿瘤的处理:一项回顾性观察研究

N. Panse, Nikhil Bhoi, Aparajita Pandey, Priyanka Dhananjay Tikait
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摘要

背景:随着IONM在神经外科应用的日益增多,静脉全麻醉在神经麻醉实践中的作用逐渐占上风。以异丙酚为基础的TIVA技术有助于快速恢复意识和精神运动功能,降低术后恶心和呕吐的发生率。它还有助于在保持足够麻醉深度的同时进行令人满意的离子离子监测。现有文献主要集中在IONM的外科方面。很少有研究将TIVA与不使用IONM的全身麻醉进行比较。在接受脊柱后凸矫正手术的患者中,早期对IONM的TIVA进行了研究。本研究旨在评估TIVA在促进IONM切除颅内肿物中的作用,并研究其对血流动力学和术后恢复的影响。方法:回顾性分析23例颅内肿瘤肿块切除手术中需用IONM的患者,给予标准全身麻醉,插管剂量为短效肌松剂,继续维持麻醉,应用异丙酚、右美托咪定等微量吸入剂输注。成功记录IONM。结果:18例患者血流动力学稳定。3例患者出现间歇性心动过缓,2例患者出现低血压。3例患者出现抑制反应,需要减少麻醉剂量。6例患者出现延迟恢复。结论:异丙酚和右美托咪定联合TIVA是一种很好的麻醉方式,可以促进IONM切除颅内肿物。
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Management of Cerebropontine Angle Tumors on Total Intravenous Anaesthesia Facilitating Neuromuscular Monitoring: A Retrospective Observational Study
Background: With the increasing trend of IONM in neurosurgery the role of total intravenous anaesthesia has gained upper hand in the practice of neuro anaesthesia. Propofol based TIVA techniques facilitates rapid recovery of consciousness and psychomotor function with lower incidence of post-operative nausea and vomiting. It also facilitates satisfactory IONM monitoring while maintaining the adequate depth of anaesthesia. Available literature focuses on the surgical aspects with IONM. Few studies are available, which compare TIVA with general anaesthesia that too without IONM. Earlier TIVA for IONM has been studied in patients undergoing kyphoscoliosis correction surgery. This study was conducted to evaluate the efficacy of TIVA in facilitating IONM in resection of intracranial masses and to study its effects on hemodynamics and post op recovery. Methods: In our retrospective study of 23 cases, patients undergoing intracranial tumor mass excision surgeries requiring IONM were given standardized general anaesthesia using intubating dose of short acting muscle relaxant and further maintenance of anaesthesia was done using infusion of propofol and dexmeditomidine with the minimal inhalational agents. IONM was recorded successfully. Results: 18 patients were haemodyanamically stable. 3 patients had intermittent episodes of bradycardia, and 2 patients had hypotension. Three patients elicited dampened response requiring reduction in anaesthetic dose. Six patients exhibited delayed recovery. Conclusion: TIVA with propofol and dexmeditomidine is a good anaesthetic modality to facilitate IONM in resection of intracranial masses.
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