慢性淋巴细胞白血病患者复发性COVID-19肺炎

E. Nasri, H. Mirhendi, B. Ataei, A. Vaezi, S. Sadeghi, H. Fakhim
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摘要

2019冠状病毒病(COVID-19)于2019年12月出现,并在全球迅速蔓延。总死亡率因地区、国家和不同患者的危险因素而异。对于许多感染,免疫功能低下的患者通常表现出非典型的体征和症状。在此,我们报告一例慢性淋巴细胞白血病(CLL)患者的SARS-CoV-19感染,并描述了该病例的临床过程、诊断和处理。最初的临床症状是呼吸困难和咳嗽,随后是喉咙痛和头痛,并进展为肺炎。42天后再次入院,伴干咳发热,无呼吸困难,静脉注射免疫球蛋白400 mg/kg体重单剂量。该病例强调了COVID-19感染在免疫功能低下患者中的重要性,这将在不同的表现和筛查程序中进行考虑。综上所述,在调查有肺炎体征和症状的CLL患者时,应追求COVID-19的鉴别诊断。
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Recurrent COVID-19 Pneumonia in Chronic Lymphocytic Leukemia Patient
The coronavirus disease 2019 (COVID-19) emerged in December 2019 and has rapidly spread worldwide. The overall mortality rate differs between regions, countries, and different patients risk factors. With many infections, immune compromised patients often present with signs and symptoms that are atypical. Herein we report a case of a SARS-CoV-19 infection in a patient with chronic lymphocytic leukemia (CLL) and describe the clinical course, diagnosis, and management of the case. The initial presenting clinical symptoms were dyspnea and cough, followed by sore throat and headache and progression to pneumonia. He was admitted once more with dry cough and fever, without dyspnea after 42 days and treated with 400 mg/kg body weight intravenous immunoglobulin (IVIG) single dose. This case highlights the importance of COVID-19 infection in immune compromised patients which would be considered in the presence of different presentation and screening procedures. In conclusion, the differential diagnosis of COVID-19 should be pursued when investigating in CLL patient with signs and symptoms of pneumonia.
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