无缝输注装置对经尿道膀胱肿瘤切除术后膀胱输注药物的影响

L. Qian, Guo Xiaoxia
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In the control group A, before instillation, a 50ml injector was also used for dissolution and suction of drug, but at the same time, the syringe nozzle was inserted into the horn-shaped catheter orifice to inject the drug. In the control group B, we used a 50 ml injector for dissolution and suction of drug before instillation and then injected to drug into an aseptic bowel. After that, we used a 50 ml medical irrigator to draw in the liquid in the bowl and inserted the irrigator nozzle into the horn-shaped catheter orifice to inject the liquid. We compared operator’s satisfaction during instillation, drug leakage and time consumption between the three groups. Results: Operator’s satisfaction in the experimental group, control group A and control group B was 100%, 12% and 84% respectively and there was a significant difference in that between the three groups (χ2=57.576, P=0.000). In terms of drug leakage, there was no leakage in the experimental group, and an average of 11.44±2.13 ml of leakage in the control group A and an average of 0.77±1.14 ml of leakage in the control group B. The one-way analysis of variance showed that there was a significant difference in that (F=1041.089, P=0.000). At last, the time consumption in the experimental group was 9.28±1.21min, and the control group A took the longest time 11.58±1.81 min. The one-way analysis of variance showed that there was a significant difference in time consumption between the three groups (F=32.947, P=0.000). Conclusions: the self-designed seamless device for instillation in the bladder instillation of drug for patients who underwent transurethral resection of bladder tumor can not only ensure the dosage of drug, avoid iatrogenic exposure but also reduce time consumption and improve medical staff’s satisfaction. 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引用次数: 0

摘要

目的:探讨无缝输注装置在经尿道膀胱肿瘤切除术后膀胱输注药物中的应用效果。方法:选取2019年1月至2019年12月泌尿外科行经尿道膀胱肿瘤切除术患者24例,随访150人次膀胱输注药物。采用随机数字表法将150人次平均分为实验组、对照组A、对照组b。实验组在膀胱输注药物前,用50ml注射器溶出吸药。在给药过程中,我们使用肝素帽将注射器与导管连接,使其成为一个无缝的给药装置。对照组A,在给药前同样使用50ml注射器进行药物溶出和吸出,同时将注射器喷嘴插入喇叭状导管口进行药物注射。对照组B在给药前先用50ml注射器将药物溶解吸出,再将药物注射到无菌肠内。然后用50ml医用冲洗器将碗内的液体吸出,将冲洗器喷嘴插入喇叭状导管口进行液体注射。比较三组操作人员对滴注过程的满意度、漏药量和时间消耗。结果:实验组、对照组A、对照组B的操作人员满意度分别为100%、12%、84%,三组间差异有统计学意义(χ2=57.576, P=0.000)。药物漏出方面,实验组无漏出,对照组A平均漏出11.44±2.13 ml,对照组b平均漏出0.77±1.14 ml。单因素方差分析显示,两组间差异有统计学意义(F=1041.089, P=0.000)。最后,实验组用时9.28±1.21min,对照组用时最长,为11.58±1.81 min。经单因素方差分析,三组用时差异有统计学意义(F=32.947, P=0.000)。结论:自行设计的经尿道膀胱肿瘤切除术患者膀胱内滴注药物无缝装置,既保证了药物用量,避免了医源性暴露,又减少了时间消耗,提高了医护人员的满意度。因此,该无缝装置值得临床应用。
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Effect of a Seamless Device for Instillation on Bladder Instillation of Drug After Transurethral Resection of Bladder Tumor
Objective: We aim to explore the effect of a seamless device for instillation on bladder instillation of drug after transurethral resection of bladder tumor. Methods: There were 24 patients undergoing transurethral resection of bladder tumor in the department of urinary surgery from January 2019 to December 2019, and 150 person-times of bladder instillation of drug in follow-up. We adopted random number table to averagely divide the 150 person-times into experimental group, control group A and control group B. In the experimental group, before bladder instillation of drug, a 50ml injector was used for dissolution and suction of drug. During instillation of drug, we used heparin cap to connect the injector and catheter to make a seamless device for instillation. In the control group A, before instillation, a 50ml injector was also used for dissolution and suction of drug, but at the same time, the syringe nozzle was inserted into the horn-shaped catheter orifice to inject the drug. In the control group B, we used a 50 ml injector for dissolution and suction of drug before instillation and then injected to drug into an aseptic bowel. After that, we used a 50 ml medical irrigator to draw in the liquid in the bowl and inserted the irrigator nozzle into the horn-shaped catheter orifice to inject the liquid. We compared operator’s satisfaction during instillation, drug leakage and time consumption between the three groups. Results: Operator’s satisfaction in the experimental group, control group A and control group B was 100%, 12% and 84% respectively and there was a significant difference in that between the three groups (χ2=57.576, P=0.000). In terms of drug leakage, there was no leakage in the experimental group, and an average of 11.44±2.13 ml of leakage in the control group A and an average of 0.77±1.14 ml of leakage in the control group B. The one-way analysis of variance showed that there was a significant difference in that (F=1041.089, P=0.000). At last, the time consumption in the experimental group was 9.28±1.21min, and the control group A took the longest time 11.58±1.81 min. The one-way analysis of variance showed that there was a significant difference in time consumption between the three groups (F=32.947, P=0.000). Conclusions: the self-designed seamless device for instillation in the bladder instillation of drug for patients who underwent transurethral resection of bladder tumor can not only ensure the dosage of drug, avoid iatrogenic exposure but also reduce time consumption and improve medical staff’s satisfaction. Hence, the seamless device is worth clinical application.
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