简述不同类型的癌症及一些草药和生物活性化合物在肺癌治疗中的作用

Roshan Kumar, Prachi Sood, Rahaman Shaik, Harjeet Singh, A. Verma
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引用次数: 1

摘要

与包括化疗、放射治疗和手术在内的金标准治疗相比,癌症免疫疗法大大提高了患者的存活率,并显著改善了患者的生活质量。免疫疗法已经牢固地确立了自己作为癌症治疗的新支柱的地位,从转移阶段一直到各种癌症类型的辅助和新辅助治疗。在这篇综述中,主要的重点将放在癌症免疫治疗历史上的开创性时刻,这些时刻为今天可用的尖端治疗铺平了道路。利用草药和从这些草药中获得的植物化合物进行癌症治疗正成为一种越来越有吸引力的选择。许多临床研究已经证明,将草药与传统疗法结合使用可以提高癌症患者的生存率、免疫调节和生活质量。除此之外,我们还重点介绍了癌症检查点免疫疗法目前面临的挑战和限制,以及在个体化癌症疫苗、自身免疫、微生物组、肿瘤微环境和代谢组学等领域正在进行的前沿研究,以寻找解决这些问题的方法。数百年来,传统医学的从业者一直依赖于从植物中提取的治疗方法。世界各地对植物的用途进行了许多研究,其中一些发现导致了从植物中提取的药物的开发。据估计,全球药用植物产品市场每年价值超过1000亿美元。本研究调查了药用植物在当前疾病预防战略方法中的作用、贡献和效用,特别是肺癌,这是一个公共卫生问题。本研究的重点是目前预防疾病的战略方法。
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A Brief Description of Different Types of Cancers and Role of Some Herbs & Bioactive Compounds in Lung Cancer Management
Cancer immunotherapy has considerably raised patient survival rates and significantly improved patients' quality of life in comparison to the gold standard of care, which includes chemotherapy, radiation therapy, and surgery. Immunotherapy has firmly established itself as a novel pillar of cancer care across the board, from the metastatic stage all the way through adjuvant and neoadjuvant treatment in a wide variety of cancer types. In this overview, the primary emphasis will be placed on the seminal moments in the history of cancer immunotherapy that prepared the way for the cutting-edge treatments that are available today. Cancer treatment that makes use of medicinal herbs and the phytocompounds that can be obtained from those herbs is becoming an increasingly attractive option. It has been demonstrated in a number of clinical studies that the use of herbal medicines in conjunction with conventional therapy can increase survival rates, immunological modulation, and quality of life (QOL) in patients who have cancer. In addition to this, we highlight the challenges and restrictions currently faced by cancer checkpoint immunotherapy as well as the cutting-edge research being conducted in the fields of individualized cancer vaccines, autoimmunity, the microbiome, the microenvironment of tumors, and metabolomics to find solutions to these problems. For hundreds of years, practitioners of traditional medicine have depended on treatments derived from plants. Many studies on their use have been carried out all over the world, and some of the findings have led to the development of medicines that are derived from plants. The global market for medicinal plant products is estimated to be worth more than one hundred billion dollars each year. This research investigates the role, contributions, and utility of medicinal plants in the context of the current strategic methods to disease prevention, notably lung cancer, which is a public health concern. The focus of this research is on the current strategic approaches to disease prevention.
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