福州市40岁以上人群慢性阻塞性肺病流行病学调查

Ming Wu, Qinhua Liu, Yongming Guo, Jihong Wang, Shao-Fen Liu, Yu Liu, Xin Liu, Shi Chen
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摘要

目的了解福州市40岁及以上人群慢性阻塞性肺疾病(COPD)的流行病学分布特征及相关危险因素,为COPD的防治提供指导。方法采用随机整群抽样的方法,对福州市鼓楼区、仓山区、金安区、台江区、马尾区5个区40岁以上人群进行调查。我们为受访者设计了一份问卷,问卷完成后进行了一些身体检查和肺功能测试。对所得数据进行copd相关的单因素和多因素统计分析。结果我们对1055名参与者进行了验证。COPD的总患病率为10.6%(112/ 1055)。男女患病率分别为13.0%(70/538)和8.1%(42/517)。多因素logistic回归分析显示,年龄(χ2=27.051, P<0.01)、性别(χ2=4.374, P<0.05)、身体质量指数(χ2=27.925, P<0.05)、吸烟(χ2=13.900, P<0.01)、儿童咳嗽史(χ2=80.580, P<0.01)、家族史(χ2=42.961, P<0.01)、室内烟雾(χ2=13.603, P<0.01)、厨房通风(χ2=12.111, P<0.05)与COPD发病风险相关。结论福州市≥40岁人群COPD总患病率为10.6%。影响慢性阻塞性肺病的主要因素为男性、年龄较大、BMI较低、吸烟、咳嗽史、呼吸系统疾病家族史、室内烟雾浓重、厨房通风不良。与COPD相关的危险因素涉及个人、家庭和社会生活的多个方面。要有针对性地开展COPD的防治工作,降低COPD的患病率,提高COPD患者的生活质量。关键词:肺部疾病;慢性阻塞性肺疾病;流行病学;风险因素;福州
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An epidemiological investigation of COPD in people aged 40 years or older in Fuzhou
Objective To investigate the epidemiological distribution characteristics and related risk factors of chronic obstructive pulmonary disease (COPD) in Fuzhou among people aged 40 years or older, and provide guidance for the prevention and treatment of COPD. Methods A random and cluster sampling method was used to survey people who older than 40 years in five districts of Fuzhou (Gulou District, Cangshan District, Jin′an District, Taijiang District and Mawei District). We designed a questionnaire for the respondents, after which, some physical examinations and lung function tests were carried out.COPD-related univariate and multivariate statistical analysis were performed on the data obtained. Results We validated 1 055 participants with available data.The overall prevalence of COPD was 10.6%(112/1 055). Male and female prevalence rates were 13.0% (70/538) and 8.1%(42/517). Age (χ2=27.051, P<0.01), gender (χ2=4.374, P<0.05), BMI (χ2=27.925, P<0.05), smoking (χ2=13.900, P<0.01), childhood cough history (χ2=80.580, P<0.01), family history (χ2=42.961, P<0.01), indoor fumes (χ2=13.603, P<0.01) and kitchen ventilation (χ2=12.111, P<0.05) were associated with the risk of COPD in the multivariate logistic regression analysis. Conclusions The total prevalence of COPD among people aged ≥40 years in Fuzhou was 10.6%.The main factors affecting COPD are male, elder, lower BMI, smoking, coughing history, family history of respiratory disease, heavy indoor fumes and poor kitchen ventilation.The risk factors related to COPD involve multiple aspects of individual, family and social life.The prevention and treatment of COPD should be carried out in a targeted manner to reduce the prevalence of COPD and improve the quality of life of COPD patients. Key words: Pulmonary disease, chronic obstructive; Epidemiology; Risk factors; Fuzhou
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