对冰毒温度反应的平衡激发和抑制

Temperature: Multidisciplinary Biomedical Journal Pub Date : 2014-10-30 DOI:10.4161/2167549X.2014.968483

Y. Molkov, D. Zaretsky

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引用次数: 6

摘要

服用各种安非他明后致死性高热是众所周知的临床现象，然而，对其病因和/或发病机制尚无一致的理论解释。甲基苯丙胺对温度反应的剂量依赖性是复杂的。最近，利用数学模型表明，兴奋和抑制机制的微妙相互作用是这种复杂性的基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Balanced excitation and inhibition in temperature responses to meth

Fatal hyperthermia after administration of various amphetamines is well-known clinical phenomenon, however, there is no consistent theory explaining its etiology and/or pathogenesis. Dose-dependence of temperature responses to methamphetamine is intricate. Recently, using mathematical modeling it was suggested that delicate interplay of excitatory and inhibitory mechanisms underlies this complexity.

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Temperature: Multidisciplinary Biomedical Journal

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