一种近场通信(NFC)无线荧光仪,用于完全植入式生物传感应用

A. Dehennis, M. Mailand, David Grice, S. Getzlaff, Arthur E. Colvin
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引用次数: 20

摘要

远程供电的生物监测系统外形小巧,可长期植入,可促进多种疾病和病症的治疗[1,2]。这种类型的传感器系统还可以建立在近场通信中使用的标准之上,这为与大多数时间保持休眠状态的无电池传感系统通信提供了很大的机会,除非被主机系统激活进行测量。本文提出了一种无线荧光仪,可实现长期植入式连续血糖监测系统。这项工作将基于荧光法的传感与微系统技术相结合,以充分利用光学效率的大幅提高,并为需要长期可靠性和小尺寸的应用提供机会。荧光转导还可以实现电气系统的完全封装,将其与外部放置的指示器隔离开来,该指示器需要与其环境保持连续平衡。
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A near-field-communication (NFC) enabled wireless fluorimeter for fully implantable biosensing applications
Remotely powered, biological-monitoring systems with a small form factor that enable long-term implantation can facilitate treatments for a variety of diseases and conditions [1,2]. This type of sensor system can also build off the standards used in near-field communications, which provide a great opportunity for communicating with battery-less sensing systems that remain dormant the majority of the time, except when activated by a host system to take measurements. This paper presents a wireless fluorimeter that enables a long-term implantable, continuous glucose-monitoring system. This work merges fluorimetry-based sensing with microsystem technology, to leverage the substantial increases in optical efficiency and provide access to applications where long-term reliability and small form factor are required [2]. Fluorescent transduction also enables full encapsulation of the electrical system, isolating it from an externally placed indicator, which needs to be in continuous equilibrium with its environment.
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