Comparison on the effects of complete mesocolic excision and traditional radical operation in the treatment of colon cancer

Objective To investigate the clinical value of complete mesocolic excision and traditional radical operation for patients with colon cancer. Methods Sixty-six colon cancer patients admitted to the Second People’s Hospital of Datong from December 2015 to September 2016 were selected and divided into control group and study group according to the random number table method, with 33 cases in each group. Patients in the study group were treated by complete mesocolic excision, while patients in the control group were treated by traditional radical operation. The operation, postoperative complications, inflammatory factors, immune function and outcomes of follow-up were compared between the two groups. Results There was no significant difference in operation time between the study group and control group (P>0.05). The volume of bleeding, time of extubation, time of first anal exhaust and postoperative hospital stay in the study group were less than those in the control group (P 0.05). The levels of C-reactive protein (CRP), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) increased in both groups 24 hours after operation, but the increases in the study group were lower than those in the control group (P 0.05). The incidence of postoperative complications in the study group (6.06%, 2/33) was lower than that in the control group (21.21%, 7/33), P<0.05. The recurrence rate (3.03%, 1/33) and mortality rate (0, 0/33) of the study group were lower than those of the control group (21.21%, 7/33; 15.15%, 5/33), P<0.05. Conclusions Complete mesocolic excision is effective and safe in the treatment of colon cancer, which is beneficial to the long-term prognosis of patient. Key words: Colon cancer; complete mesocolic excision; Traditional radical operation