大角牛角花的生物化学特征

M. Ferdosi, Iqra Khan, A. Javaid, A. Munir
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引用次数: 4

摘要

鹿角草是鹿角草科的一种药用杂草。本研究对采自巴基斯坦旁遮普南部地区的C. procera花的生化特征进行了研究。采用气相色谱-质谱联用技术对牛蒡花甲醇提取物进行分析。在该提取物中鉴定出30种化合物。主要化合物为γ-谷甾醇,峰面积为15.39%。其他含量丰富的化合物包括豆甾醇(9.22%)、9,12-十八烯二酸(Z,Z)-甲酯(9.01%)、油菜籽醇(8.63%)、α-醋酸amyrin(8.25%)、β-amyrin(8.09%)、十六烷酸甲酯(7.91%)、11-十八烯酸甲酯(6.15%)和2-甲氧基-4-乙烯基酚(5.66%)。中等含量的化合物包括壬烷-1-烯(2.83%)、硬脂酸甲酯(1.57%)、五烷(1.44%)、叶绿醇(1.33%)、七烷-1-烯(1.20%)、十六烷(1.19%)和六烷(1.09%)。其余丰度较低的化合物存在,峰面积小于1%。文献调查表明,从黄果仁花提取物中鉴定出的主要化合物具有抗糖尿病、抗癌、降血糖、抗氧化、抗菌和抗炎等多种生物活性。
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BIOCHEMICAL PROFILE OF Calotropis procera FLOWERS
Calotropis procera is a medicinal weed of family Asclepiadaceae. This study was carried out to explore the biochemical profile of C. procera flowers collected from Southern Punjab region of Pakistan. Methanolic flower extract of C. procera was subjected to GC-MS analysis. There were 30 compounds identified in this extract. The predominant compound was γ-sitosterol with 15.39% peak area. Other abundantly occurring compounds included stigmasterol (9.22%), 9,12-octadecadienoic acid (Z,Z)-, methyl ester (9.01%), campesterol (8.63%), α-amyrin acetate (8.25%), β-amyrin (8.09%), hexadecanoic acid, methyl ester (7.91%), 11-octadecenoic acid, methyl ester (6.15%), and 2-methoxy-4-vinylphenol (5.66%). Moderately abundant compounds included nonacos-1-ene (2.83%), methyl stearate (1.57%), pentacosane (1.44%), phytol (1.33%), heptacos-1-ene (1.20%), heneicosane (1.19%), and 1-hexacosene (1.09%). The remaining less abundant compounds were present with peak areas less than 1%. Literature survey showed that the major compounds identified in the flower extract of C. procera possess various bioactivities including antidiabetic, anticancer, antihyperglycemic, antioxidant, antimicrobial and anti-inflamatory.
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