肉桂萃取物包覆银纳米颗粒的绿色合成及其生物学应用

Sajina Narath, S. Shankar, Saranya Kothaplamoottil Sivan, Bini George, T. D. Thomas, S. Sabarinath, Sajithkumar K. Jayaprakash, S. Wacławek, V. Padil
{"title":"肉桂萃取物包覆银纳米颗粒的绿色合成及其生物学应用","authors":"Sajina Narath, S. Shankar, Saranya Kothaplamoottil Sivan, Bini George, T. D. Thomas, S. Sabarinath, Sajithkumar K. Jayaprakash, S. Wacławek, V. Padil","doi":"10.2478/eces-2023-0001","DOIUrl":null,"url":null,"abstract":"Abstract The plant mediated biogenic synthesis of nanoparticles is of magnificent concern due to its eco-benign and single pot nature. Here, Cinnamomum tamala (C. tamala) aqueous leaf extract was utilised for the silver nanoparticles’ (Ag NPs) synthesis. The phytoconstituents in the leaf extract were analysed by standard methods. These metabolites, especially carbohydrate polymers reduce Ag ions to Ag NPs accompanied by a reddish-brown coloration of the reaction mixture. The visual observation of intense brown colour is the first indication of the formation of Ag NPs. Various spectro-analytical techniques further characterise the Ag NPs. The green synthesised spherical Ag NPs were crystalline with an average size of 38 nm. The Ag NPs were scrutinised for antioxidant, antimicrobial and cytotoxic activity and obtained good results. The free radical scavenging was studied by 2, 2-Diphenyl-l-picrylhydrazyl (DPPH) assay. The antibacterial activity of Ag NPs was assessed against human pathogens, and it shown to have good antibacterial potency against a wide spectrum of bacteria. The cytotoxic activity against HEK-293T (human embryonic kidney) cell line was evaluated by 2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide (XTT) assay. These potent biological activities enable C. tamala capped Ag NPs to be suitable candidates for the future applications in various fields, predominantly clinical and biomedical.","PeriodicalId":11395,"journal":{"name":"Ecological Chemistry and Engineering S","volume":"40 1","pages":"7 - 21"},"PeriodicalIF":0.0000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Facile Green Synthesis of Cinnamomum tamala Extract Capped Silver Nanoparticles and its Biological Applications\",\"authors\":\"Sajina Narath, S. Shankar, Saranya Kothaplamoottil Sivan, Bini George, T. D. Thomas, S. Sabarinath, Sajithkumar K. Jayaprakash, S. Wacławek, V. Padil\",\"doi\":\"10.2478/eces-2023-0001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract The plant mediated biogenic synthesis of nanoparticles is of magnificent concern due to its eco-benign and single pot nature. Here, Cinnamomum tamala (C. tamala) aqueous leaf extract was utilised for the silver nanoparticles’ (Ag NPs) synthesis. The phytoconstituents in the leaf extract were analysed by standard methods. These metabolites, especially carbohydrate polymers reduce Ag ions to Ag NPs accompanied by a reddish-brown coloration of the reaction mixture. The visual observation of intense brown colour is the first indication of the formation of Ag NPs. Various spectro-analytical techniques further characterise the Ag NPs. The green synthesised spherical Ag NPs were crystalline with an average size of 38 nm. The Ag NPs were scrutinised for antioxidant, antimicrobial and cytotoxic activity and obtained good results. The free radical scavenging was studied by 2, 2-Diphenyl-l-picrylhydrazyl (DPPH) assay. The antibacterial activity of Ag NPs was assessed against human pathogens, and it shown to have good antibacterial potency against a wide spectrum of bacteria. The cytotoxic activity against HEK-293T (human embryonic kidney) cell line was evaluated by 2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide (XTT) assay. These potent biological activities enable C. tamala capped Ag NPs to be suitable candidates for the future applications in various fields, predominantly clinical and biomedical.\",\"PeriodicalId\":11395,\"journal\":{\"name\":\"Ecological Chemistry and Engineering S\",\"volume\":\"40 1\",\"pages\":\"7 - 21\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ecological Chemistry and Engineering S\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2478/eces-2023-0001\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ecological Chemistry and Engineering S","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2478/eces-2023-0001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

摘要植物介导的纳米颗粒生物合成因其生态无害和单罐性而备受关注。本研究以塔玛拉肉桂(C. tamala)叶片水提物为原料合成纳米银。采用标准方法对叶提取物中的植物成分进行了分析。这些代谢物,特别是碳水化合物聚合物将银离子还原为银NPs,并伴有反应混合物的红褐色。肉眼观察到的深棕色是银NPs形成的第一个迹象。各种光谱分析技术进一步表征了银纳米粒子。绿色合成的球形银纳米粒子呈结晶状,平均尺寸为38 nm。对银NPs进行了抗氧化、抗菌和细胞毒活性检测,获得了良好的结果。采用2,2 -二苯基-l-苦味酰肼(DPPH)法研究其自由基清除能力。测定了银NPs对人体病原菌的抑菌活性,结果表明,银NPs对多种细菌具有良好的抑菌活性。采用2,3-二-(2-甲氧基-4-硝基-5-巯基)- 2h -四氮唑-5-羧基苯胺(XTT)法测定其对人胚胎肾细胞株HEK-293T的细胞毒活性。这些有效的生物活性使C. tamala封顶的Ag NPs成为未来应用于各个领域的合适候选人,主要是临床和生物医学。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Facile Green Synthesis of Cinnamomum tamala Extract Capped Silver Nanoparticles and its Biological Applications
Abstract The plant mediated biogenic synthesis of nanoparticles is of magnificent concern due to its eco-benign and single pot nature. Here, Cinnamomum tamala (C. tamala) aqueous leaf extract was utilised for the silver nanoparticles’ (Ag NPs) synthesis. The phytoconstituents in the leaf extract were analysed by standard methods. These metabolites, especially carbohydrate polymers reduce Ag ions to Ag NPs accompanied by a reddish-brown coloration of the reaction mixture. The visual observation of intense brown colour is the first indication of the formation of Ag NPs. Various spectro-analytical techniques further characterise the Ag NPs. The green synthesised spherical Ag NPs were crystalline with an average size of 38 nm. The Ag NPs were scrutinised for antioxidant, antimicrobial and cytotoxic activity and obtained good results. The free radical scavenging was studied by 2, 2-Diphenyl-l-picrylhydrazyl (DPPH) assay. The antibacterial activity of Ag NPs was assessed against human pathogens, and it shown to have good antibacterial potency against a wide spectrum of bacteria. The cytotoxic activity against HEK-293T (human embryonic kidney) cell line was evaluated by 2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide (XTT) assay. These potent biological activities enable C. tamala capped Ag NPs to be suitable candidates for the future applications in various fields, predominantly clinical and biomedical.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Determination of Cd, Pb and Zn in Polymers by Laser Ablation Microwave Induced Plasma Optical Emission Spectrometry Ecovoltaics - A Truly Ecological and Green Source of Renewable Goods Separation Technology of Components of Waste Pharmaceutical Blisters Environmental Benefits of Green Buildings with BIM Technology Research on Ecologicultural Environment Under the Background of Rural Revitalisation
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1