伊热夫斯克医院儿童混合感染的临床和病因学特征

T. A. Britkova, K. E. Panteleev, O. A. Pazinenko
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引用次数: 1

摘要

目的:探讨现阶段儿童混合性感染的结构、特点及治疗方法。材料和方法。检查了85例5个月至17岁和10个月的儿童病史,最终诊断包括2次或更多感染,根据伊热夫斯克市第七临床医院儿童传染病科。患有急性感染性病理(急性肠道感染、急性呼吸道感染、疱疹感染)的儿童在该院住院。诊断方法:聚合酶链反应,ELISA,细菌学。混合感染在男孩和女孩中同样常见,而混合感染在幼儿(1岁以下和1岁至3岁)中占主导地位,占62.4%。感染发病结构始终以急性肠道感染(83.5%)和急性呼吸道感染(53.0%)为主。sars - cov -2相关和疱疹相关混合感染的进展以临床表现的明显多态性为特征。各病种的病因仅为17.7%;在43.5%的病例中,只有一种病因在实验室得到证实;38.8%的病例未在实验室确认病因。
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Clinical and etiological characteristics of mixed infections in children in the Izhevsk hospital
Aim: to study the structure, features of the findings and treatment of mixed infections in children at the present stage.Materials and methods. 85 case histories of children aged 5 months to 17 years and 10 months were examined, the final diagnosis of which included 2 or more infections on the basis of the children's infectious diseases department City Clinical Hospital № 7 of Izhevsk. Children with acute infectious pathology (acute intestinal infections, acute respiratory infections, herpes infections) are hospitalized in this hospital. Diagnostic methods: polymerase chain reaction, ELISA, bacteriological.Results. Mixed infections are equally common in both boys and girls, while there is a predominance of mixed infections in young children (up to 1 year and from 1 year to 3 years) 62.4%. The structure of infectious morbidity is consistently dominated by acute enteric infection – 83.5% cases and acute respiratory infections – 53.0% cases. The progression of SARS-CoV-2-associated and herpes-associated mixed infections is characterized by a pronounced polymorphism of clinical manifestations. The etiological factor for each nosology was deciphered only in 17.7%; in 43.5% of cases, only one etiological factor was verified in the laboratory; in 38.8% of cases, no etiological factor was confirmed in the laboratory.
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