尿路致病性铜绿假单胞菌的抗生素耐药性

M. Ibrahim, N. Radi, A. Al Azab
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引用次数: 0

摘要

毒力和耐药菌株铜绿假单胞菌是妇女尿路感染的最重要原因之一。本研究旨在探讨从因尿路感染住院的妇女身上分离到的铜绿假单胞菌多重耐药菌株的毒力因子频率。从患有尿路感染的女性患者中收集了100份尿液样本。培养样品,分析铜绿假单胞菌阳性的样品是否存在假定的毒力基因。100份样品中62份(62/100%)铜绿假单胞菌阳性。铜绿假单胞菌的月患病率、性别和年龄依赖性。菌株对青霉素(26.6%)、亚胺培南(26.6%)和甲氧苄啶(26.6%)的耐药水平最高。62株铜绿假单胞菌中有25株(40.3%)对10种以上抗生素耐药。我们的研究结果应该提高对住院女性尿路感染患者抗生素耐药性的认识。临床医生在开抗生素处方时应谨慎,尤其是在尿路感染的情况下。
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Antibiotic Resistance of Uropathogenic Pseudomonas Aeruginosa
Virulent and resistant strains Pseudomonas aeruginosa is one of the most important causes of UTIs in women. The present study was carried to investigate the frequency of virulence factors in the multi-drug resistant strains of P. aeruginosa isolated from women hospitalized due to the UTIs. One hundred urine samples were collected from women patients suffered from UTIs. Samples were cultured and those that were P. aeruginosa positive were analyzed for the presence of putative virulence genes. Sixty two of 100 samples (62/100%) were positive for P. aeruginosa. Monthly, sex and age-dependent prevalence were seen for P. aeruginosa. Bacterial strains had the highest levels of resistance against penicillin (26.6%), imipenem (26.6%) and Trimethoprim (26.6%). Of 62 P. aeruginosa isolates, 25 strains were resistant to more than 10 antibiotics (40.3%). Our findings should raise awareness about antibiotic resistance in hospitalized women with UTIs. Clinicians should exercise caution in prescribing antibiotics, especially in cases of UTIs.
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