埃塞俄比亚西南部吉马大学医学中心收治的成年患者脑卒中病理亚型和诊断方案

Ginenus Fekadu, Legesse Chelkeba, Tsegaye Melaku, E. Tegene
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引用次数: 12

摘要

背景:在现代治疗中风患者的方法中,早期计算机断层扫描(CT)是诊断中风是缺血性还是出血性的必要条件。脑卒中的临床诊断并不总是与影像学相关;当局限于特定脑卒中亚型的临床诊断时,情况就更糟了,这给患者的发病率和死亡率带来了很高的可能性。患者与方法:于2017年3月10日至7月10日在吉马大学医学中心脑卒中科室进行前瞻性观察研究。结果:在116例患者中,61例(52.6%)患者进行了脑部CT扫描,而其余(47.4%)患者在临床单独评估为脑卒中。按照世界卫生组织(WHO)的标准,51.7%的患者发生缺血性卒中,48.3%的患者发生出血性卒中,其中颅内出血(ICH)和蛛网膜下腔出血(SAH)分别占44.0%和4.3%。到达医院后进行CT扫描的中位时间为4天。出血性脑卒中患者最常见的脑损伤部位为基底节区(48.4%),其次为顶叶(29.0%)和脑室(29.0%)。最常见的脑梗死部位为顶叶(33.3%)和皮质(33.3%),其次为基底节区(23.3%)和尾状核(20.0%)。CT扫描显示出血性脑卒中和缺血性脑卒中患者仅表现为肺实质内出血(IPB)(61.3%)和右半球受累(26.7%)。在急性卒中治疗(TOAST)标准中,Org 10172试验的主要卒中病因为未确定病因,26例(43.3%),主要是由于评估不完整。结论:由于缺乏系统的心脏学检查和脑成像,中风的病因调查很少进行,大部分时间是由于经济原因和仪器不可用。因此,在可能的情况下,CT扫描/ MRI应纳入卒中诊断和管理。
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Pathological Sub Types and Diagnostic Protocols of Stroke among Adult Patients Admitted to Jimma University Medical Center, South West Ethiopia
Background: In the modern approach in treating patients with strokes requires early Computed Tomography (CT) scan as it is imperative to diagnose whether the stroke is ischemic or hemorrhagic. Clinical diagnosis of stroke does not always correlate with imaging; this is even worse when narrowed to clinical diagnosis of specific stroke subtype, creating a high potential for patient morbidity and mortality. Patients and methods: Prospective observational study was carried at stroke unit of Jimma University Medical Center from March 10-July 10, 2017. Result: Of the total 116 patients, 61 patients (52.6%) had CT scan of the brain performed, whereas the remaining (47.4 %) of patients were evaluated clinically alone to have stroke. Using World health organization (WHO) criteria, 51.7% patients had ischemic stroke while 48.3% had hemorrhagic, with Intracerebral Hemorrhage (ICH) and Subarachnoid Hemorrhage (SAH) accounting for 44.0% and 4.3%, respectively. The median time to perform CT scan after hospital arrival was 4 days. The most common site of lesion of brain of hemorrhage stroke patients was basal ganglia (48.4%) followed by parietal lobe (29.0%) and ventricular (29.0%). The most common site of brain infarct was parietal lobe (33.3%) and cortical (33.3%), followed by basal ganglia (23.3%) and caudate nucleus (20.0%). On CT scan majority of hemorrhagic and ischemic stroke patients had Intraparenchymal Bleed (IPB) only (61.3%) and right hemisphere involvement (26.7%) respectively. The predominant stroke etiology as Trial of Org 10172 in Acute Stroke Treatment (TOAST) criteria was undetermined etiology, 26 (43.3%), mainly because of incomplete evaluation. Conclusion: Etiologic investigation for stroke was infrequently performed by the lack of systematic cardiological examinations and brain imaging, most of the time for financial reasons and unavailability of the instruments. It is therefore, pertinent that CT scan/ MRI should be incorporated in stroke diagnosis and management where possible.
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