体积调制电弧治疗技术在halcyon上的颅脊髓照射

Shubhangi Barsing, Anand Parab, Anuradha Singh, G. Pemmaraju
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引用次数: 1

摘要

目的:颅脑脊髓照射(CSI)由于其视野大小(28cm × 28cm)的限制,是一项具有挑战性的任务。CSI是通过体积调制电弧治疗(VMAT)技术在Halcyon (6MV)直线加速器上规划的,根据患者的长度,无结移位,有多个电弧和多个等中心。方法与材料:在Eclipse治疗计划系统15.6版上采用各向异性分析算法实现计划CSI,并采用自羽化技术进行优化。通过在辐射前获取每日kvCBCT来保证定位精度,保证了准确的现场定位和避免了连接误差。为了确保治疗计划系统计算出的剂量分布与给病人的剂量相匹配,进行了预处理门静脉剂量测定。结果:所有VMAT CSI方案均产生了出色的规划靶体积(PTV)覆盖率(V95% >98%),并在所有CSI病例中给予危险器官可接受的剂量。剂量分布高度均匀,均匀性指数值≤0.1,靶区符合性同样优异,均大于0.95。在门静脉剂量学中,对所有CSI平面图的合成图像进行评估,获得了>98%的良好合格标准。结论:由于自动羽化优化,补救措施的计划和实施是直截了当的。CSI计划的创建没有结移位,这导致PTV的均匀和适形剂量。用于预处理验证的门脉剂量学复合图像中的伽马分析满足所有要求,并显示出均匀和均匀的结剂量。
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Craniospinal irradiation by volumetric modulated arc therapy technique on halcyon
Aims: Craniospinal irradiation (CSI) is a challenging task on halcyon due to its field size constraint (28 cm × 28 cm). CSI was planned by volumetric modulated arc therapy (VMAT) technique on Halcyon (6MV) linac with no junction shift with multiple arcs and numerous isocenter depending on the length of the patients. Methods and Materials: Planning CSI was achieved on Eclipse treatment planning system version 15.6 with anisotropic analytical algorithm and was optimized using autofeathering technique. Positioning accuracy was ensured by obtaining daily kvCBCT before radiation which ensured accurate field placement and avoidance of junctional errors. Pretreatment portal dosimetry was done to ensure the dose distribution calculated by the treatment planning system matches the dose delivered to the patient. Results: All VMAT CSI plans produced outstanding planning target volume (PTV) coverage with V95% >98% and gave acceptable doses to organ at risk in all CSI cases. Furthermore, the dose distributions were highly uniform, with homogeneity index values ≤0.1 and target conformity was equally excellent with values more than 0.95. In portal dosimetry, all of the composite images of CSI plans were evaluated, yielding good passing criteria of >98%. Conclusions: The remedy was straightforward to plan and deliver, thanks to autofeathering optimization. CSI plan was created with no junction shift which resulted in homogeneous and conformal doses to the PTV. The gamma analysis in the portal dosimetry composite image, which was utilized as a pretreatment verification, met all of the requirements and revealed a homogeneous and uniform junction dose.
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