脂蛋白检测:改进特征集的混合深度分类模型

IF 0.6 Q4 COMPUTER SCIENCE, THEORY & METHODS Multiagent and Grid Systems Pub Date : 2023-02-03 DOI:10.3233/mgs-220329
P. N. Kathavate, J. Amudhavel
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引用次数: 0

摘要

慢性肝病患者通常会出现血脂问题,肝硬化并发门静脉血栓(PVT)的死亡率非常高。脂蛋白(Lp)是一种生物化学组合物,其主要工作是在水中移动疏水的脂肪分子。脂蛋白存在于所有真细菌的细胞壁中。脂蛋白在螺旋体致病机制的研究中具有重要意义。由于螺旋体脂盒序列比其他细菌更具延展性,因此很难将现有的预测方法应用于新的序列数据。主要目标是提出一种脂蛋白检测模型,其中提取了相关特征、增强的对数能量熵、原始特征和语义相似特征。这些提取的特征通过门控循环单元(GRU)和长短期记忆(LSTM)相结合的混合模型进行处理。然后,对GRU和LSTM的输出进行平均,得到输出。在这里,GRU的权重是通过自私的Henry气体溶解度优化和立方映射初始化(SHGSO)模型来优化的。
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Lipoprotein detection: Hybrid deep classification model with improved feature set
Patients with chronic liver diseases typically experience lipid profile problems, and mortality from cirrhosis complicated by portal vein thrombosis (PVT) is very significant. A lipoprotein (Lp) is a bio-chemical assemblage with the main job of moving fat molecules in water that are hydrophobic. Lipoproteins are present in all eubacterial walls. Lipoproteins are of tremendous interest in the study of spirochaetes’ pathogenic mechanisms. Since spirochaete lipobox sequences are more malleable than other bacteria, it’s proven difficult to apply current prediction methods to new sequence data. The major goal is to present a Lipoprotein detection model in which correlation features, enhanced log energy entropy, raw features, and semantic similarity features are extracted. These extracted characteristics are put through a hybrid model that combines a Gated Recurrent Unit (GRU) and a Long Short-Term Memory (LSTM). Then, the outputs of GRU and LSTM are averaged to obtain the output. Here, GRU weights are optimized via the Selfish combined Henry Gas Solubility Optimization with cubic map initialization (SHGSO) model.
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来源期刊
Multiagent and Grid Systems
Multiagent and Grid Systems COMPUTER SCIENCE, THEORY & METHODS-
CiteScore
1.50
自引率
0.00%
发文量
13
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