{"title":"片剂生产过程中存在的问题及评价试验综述","authors":"Shehnaz Khatoon, Anmolpreet Singh, Pankaj Kumar, Masrror Hashmi","doi":"10.55544/jrasb.2.3.26","DOIUrl":null,"url":null,"abstract":"Tablets are the traditional over all medicinal dosage forms for solid dosages. A tablet is a solid pharmaceutical dosage form that is typically manufactured by compressing or moldings the medicinal component with appropriate diluents. They are easier to create than any other dosage form, but during manufacturing, a number of issues may occur that force the batch to be discarded. Post compression studies are also crucial before the dosage forms are put on the market. Modern standards and concepts that emphasize bioavailability, bioequivalence, and validation, among other things, have an impact on formulation design and production. In this article, we discussed the issues (Picking, Sticking, Mottling, etc.) that will arise during the production of tablets, their solutions, as well as the pre- and post- Compression qualities (such as hardness, thickness, and weight variation) and the upper limitations of their use in commercial dosage forms.","PeriodicalId":13755,"journal":{"name":"International Journal For Research in Applied Sciences and Biotechnology","volume":"82 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Review Article on Inprocess Problems and Evaluation Tests of Tablets Manufacturing\",\"authors\":\"Shehnaz Khatoon, Anmolpreet Singh, Pankaj Kumar, Masrror Hashmi\",\"doi\":\"10.55544/jrasb.2.3.26\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Tablets are the traditional over all medicinal dosage forms for solid dosages. A tablet is a solid pharmaceutical dosage form that is typically manufactured by compressing or moldings the medicinal component with appropriate diluents. They are easier to create than any other dosage form, but during manufacturing, a number of issues may occur that force the batch to be discarded. Post compression studies are also crucial before the dosage forms are put on the market. Modern standards and concepts that emphasize bioavailability, bioequivalence, and validation, among other things, have an impact on formulation design and production. In this article, we discussed the issues (Picking, Sticking, Mottling, etc.) that will arise during the production of tablets, their solutions, as well as the pre- and post- Compression qualities (such as hardness, thickness, and weight variation) and the upper limitations of their use in commercial dosage forms.\",\"PeriodicalId\":13755,\"journal\":{\"name\":\"International Journal For Research in Applied Sciences and Biotechnology\",\"volume\":\"82 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal For Research in Applied Sciences and Biotechnology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.55544/jrasb.2.3.26\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal For Research in Applied Sciences and Biotechnology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.55544/jrasb.2.3.26","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Review Article on Inprocess Problems and Evaluation Tests of Tablets Manufacturing
Tablets are the traditional over all medicinal dosage forms for solid dosages. A tablet is a solid pharmaceutical dosage form that is typically manufactured by compressing or moldings the medicinal component with appropriate diluents. They are easier to create than any other dosage form, but during manufacturing, a number of issues may occur that force the batch to be discarded. Post compression studies are also crucial before the dosage forms are put on the market. Modern standards and concepts that emphasize bioavailability, bioequivalence, and validation, among other things, have an impact on formulation design and production. In this article, we discussed the issues (Picking, Sticking, Mottling, etc.) that will arise during the production of tablets, their solutions, as well as the pre- and post- Compression qualities (such as hardness, thickness, and weight variation) and the upper limitations of their use in commercial dosage forms.