腹部手术后的镇痛:静脉注射vs连续胸椎硬膜外疼痛管理

G. Enten, Suvikram Puri, M. Copeland, D. Mangar, E. Camporesi
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摘要

简介/背景:本研究评估了连续胸廓硬膜外镇痛(TEA)与静脉镇痛方法对常见腹腔镜腹部手术麻醉需求的影响。坦帕总医院2017年新指南的引入为这两种疼痛管理方法的连续病例系列分析提供了机会。方法:对接受腹腔镜或机器人辅助腹部手术的患者进行连续病例系列。患者是根据外科医生的要求,使用相同的护士和住院支持团队招募的。数据来自当地IRB批准后的回顾性图表回顾,并评估静脉镇痛与连续T9-10硬膜外镇痛的效果。主要结局是术中、24小时和24小时后阿片类药物使用吗啡毫克当量(MME)。同时收集住院时间和VAS疼痛评分。结果:两组患者年龄、性别、BMI均无显著差异。相比之下,接受硬膜外麻醉的患者在术后24小时内疼痛评分明显降低(p<0.05),在剩余的住院时间内疼痛评分明显降低(p<0.05)。PACU (p<0.001)、术后前24小时(p<0.001)和每日用药总量(p<0.01)麻醉需用量均显著降低。结论:对于接受普通腹腔镜手术的患者,持续胸腔硬膜外镇痛是静脉镇痛的可行选择。需要进一步的研究来确定TEA用于腹腔镜结直肠手术的风险和益处。
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Analgesia Post Abdominal Surgery: Intravenous vs. Continuous Thoracic Epidural Pain Management
Introduction/Background: This study evaluates the effects of continuous thoracic epidural analgesia (TEA) vs. intravenous pain control methods on the narcotics requirement for common laparoscopic abdominal surgeries. The introduction of new guidelines at Tampa General Hospital for the year 2017 afforded the opportunity for a sequential case series analysis of these two methods of pain management. Methods: A sequential case-series on patients undergoing laparoscopic or robot assisted abdominal surgery was performed. Patients were recruited upon request of surgeons using the same nurses and resident support team. Data were obtained from retrospective chart review following local IRB approval and evaluated for the effects of intravenous analgesia compared to continuous T9-10 epidural analgesia. Primary outcomes were intraoperative, 24 h and post-24 h opioid use in morphine milligram equivalents (MME). Length of hospital stay and VAS pain scores were also collected. Results: There was no significant difference in terms of age, gender, and BMI between groups. When compared patients who received epidural reported significantly lower pain scores in the first 24 h after surgery (p<0.05) and for the remainder of their hospital stay (p<0.05). Significant decreases in narcotic requirement was noted in the PACU (p<0.001), the first 24 h after surgery (p<0.001), and aggregate use per day (p<0.01). Conclusions: Continuous thoracic epidural analgesia is a viable alternative to intravenous pain control for patients undergoing common laparoscopic surgeries. Further research is required to determine the risks and benefits of TEA for laparoscopic colorectal surgery.
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