Meek微移植技术在资源有限的情况下降低大面积烧伤患者的死亡率和住院时间

N. Wanjala, Ogallo John Paul, Ochieng Raduma Sephania
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引用次数: 2

摘要

烧伤会导致严重的死亡率。高死亡率的原因之一是烧伤创面处理不当,特别是大面积烧伤和供体部位有限的患者。大多数资源有限的国家没有同种异体移植物或组织培养,这将使这种伤口能够迅速和容易地覆盖。像Meek微移植物这样的皮肤采集技术被认为是昂贵的,因此不可用。因此,在许多资源有限的国家,大面积烧伤的患者预后不佳,死亡率高,住院时间长。本研究是一项前瞻性研究,研究对象是肯尼亚某三级教学医院采用meek显微移植技术进行大面积烧伤手术的患者。分析的变量包括:总烧伤面积、皮肤移植次数、住院时间、供体部位发病率和死亡率。在过去的三年中,我们对25例大面积烧伤患者进行了显微移植。患者平均总烧伤面积为46.7%,范围为24% ~ 72%。5名患者在接受治疗期间死亡,死亡率为20%,而我们中心报告的使用补片技术治疗相似烧伤面积的患者死亡率为35%。平均住院时间为73.92天,而此前报道的住院时间为97.4天。供体平均表面积为15.8%。平均愈合时间为16.7 d。3例患者供体部位伤口败血症,用银基敷料敷料后愈合。Meek微型移植技术允许用相对较小的供体大面积覆盖烧伤创面。该技术与减少供体部位的发病率、死亡率和住院时间有关。这种技术应该在发展中国家的许多烧伤中心得到鼓励,因为那里有大面积烧伤的病人。
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Meek Micro-grafting Technique in Reduction of Mortality and Hospital Stay in Patients With Extensive Burns in a Resource Constrained Setting
Burns contributes to significant mortality. Among reasons for high mortality is inadequate burn wound management especially in patients with extensive burns and limited donor sites. Majority of the resource constrained countries donot have allografts or tissue cultures that would enable prompt and easy cover ages of such wounds. Skin graft Harvesting techiques such as the Meek micrografts are considered expensive and are thus not available. Patients with extensive burn wounds in many resource constrained countries as a result of this do have poor outcomes with high mortality and prolonged hospital stay. This was a prospective study on patients with extensive burns operated on with theMeek micro-grafting technique in a tertiary teaching Hospital in Kenya. Variables analysed included, total burn surface area, sessions of skin grafts, length of Hospital stay, donor site morbidity and mortality. Twenty five patients with extensive burn wounds were managed with the micro grafting technique over the last three years. The mean total burn surface area for the patients was 46.7 percent with the range of 24 to 72 percent. Five patients died while undergoing treatment giving a mortality rate of 20 percent compared to a mortality rate of 35 percent reported in our centre for patients with the similar burn surface area operated on with the mesh technique. The mean length of Hospital stay was 73.92 days compared to a Hospital stay length of 97.4 days previously reported prior to this technique. The mean donor size surface area was 15.8%. The average length of time the donorsite wounds healed was 16.7 days. Three patients had wound sepsis at the donor site that healed after dressing with silver based dressing materials. Meek micro grafting technique allows for extensive coverage of burn wounds with a relatively small donorsite. The technique is associated with reduced donor site morbidity, mortality and length of Hospital stay. This technique should be encouraged in many burn centers in developing countries where there are patients with extensive burn wounds.
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