脑动脉瘤支架置入术前后血管造影染色冲洗的建模:支架疗效的指标

C. Sadasivan, B. Lieber, D. Lopes, A. Ringer, L. Hopkins
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引用次数: 1

摘要

治疗脑动脉瘤的最终目的是在保留母动脉的同时将其排除在颅内循环之外。近年来,体内、体外实验和临床研究表明,血管内支架植入术是治疗脑动脉瘤的重要且可行的选择。支架减少了从载动脉到动脉瘤的血液的质量和动量运输,并改变了动脉瘤内的流动和流入-流出模式。囊内涡度和血流停滞的减少导致血栓形成,并最终将动脉瘤排除在循环之外。数字减影血管造影(DSA)已成为诊断和治疗动脉瘤的重要临床工具,是支架手术的重要辅助手段。
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Modeling of Angiographic Dye Washout From Cerebral Aneurysms Before and After Stenting: An Index for Stent Efficacy
The ultimate goal in the treatment of cerebral aneurysms is to exclude them from the intracranial circulation while preserving the parent artery. Recently, in vivo and in vitro experiments and clinical studies demonstrated that endovascular stenting is a significant and viable treatment option for cerebral aneurysms. Stents reduce the mass and momentum transport of blood from the parent artery into the aneurysm and alter both intra-aneurysmal flow and inflow-outflow patterns. The reduction of vorticity and flow stasis within the sac leads to thrombus formation and eventual exclusion of the aneurysm from the circulation. Digital subtraction angiography (DSA) has become an essential clinical tool for the diagnosis and treatment of aneurysms and is an important adjunct to stenting procedures.
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