Diphoterine solution decontamination of eye/skin chemical exposures: Review and update on recent data

Introduction: Diphoterine is an amphoteric, slightly hypertonic, polyvalent, sterile water-based eye/skin decontamination solution which combines passive flushing with active chemical decontamination. Reviews were published in French (Minaro et al, 2000) and Hall et al (2002). Since that time, many more studies of Diphoterine safety and efficacy, both pre-clinical and clinical, have been performed. This review describes earlier studies and details more current ones. Some of these were described in reviews at the Medichem Conference, Basel, Switzerland, 2016, at the AMPAT Congress, Singapore, 2016, and the AOHC Congress, Kaohsiung, Taiwan. Presented here are new not previously presented data.