{"title":"低强度(0.2T)静磁场对人胶质母细胞瘤细胞核固结环的分散作用","authors":"S. C. Kim, W. Im, Beom Jin Kim","doi":"10.4172/2155-9562.1000429","DOIUrl":null,"url":null,"abstract":"Biomagnetism is one of important biotechnology fields for manipulation of cell lines. However, its peri-cellular level regulation, upon stimulation is not fully developed. Glioblastoma U87 and U251 represent a malignant model in rapid growing cancer. We focused in cellular level dispersion of static magnetic fields (0.2T=2000 ± 600 Gauss), using its fast growing properties. As a result, cytoskeletal protein nuclear Ankyrin G was dispersed. Membrane barriers in TEM microscopy indicated the membranous apparatus change. Our findings bring an insight that static magnetic stimulation creates a specified cytoplasmic intracellular pattern","PeriodicalId":16455,"journal":{"name":"Journal of Neurology and Neurophysiology","volume":"9 1","pages":"1-6"},"PeriodicalIF":0.0000,"publicationDate":"2017-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Low Intensity (0.2T) Static Magnetic Field for Dispersing Nucleus AnkyrinG in Human Cultured Glioblastoma Cells\",\"authors\":\"S. C. Kim, W. Im, Beom Jin Kim\",\"doi\":\"10.4172/2155-9562.1000429\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Biomagnetism is one of important biotechnology fields for manipulation of cell lines. However, its peri-cellular level regulation, upon stimulation is not fully developed. Glioblastoma U87 and U251 represent a malignant model in rapid growing cancer. We focused in cellular level dispersion of static magnetic fields (0.2T=2000 ± 600 Gauss), using its fast growing properties. As a result, cytoskeletal protein nuclear Ankyrin G was dispersed. Membrane barriers in TEM microscopy indicated the membranous apparatus change. Our findings bring an insight that static magnetic stimulation creates a specified cytoplasmic intracellular pattern\",\"PeriodicalId\":16455,\"journal\":{\"name\":\"Journal of Neurology and Neurophysiology\",\"volume\":\"9 1\",\"pages\":\"1-6\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-06-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Neurology and Neurophysiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4172/2155-9562.1000429\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Neurology and Neurophysiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2155-9562.1000429","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Low Intensity (0.2T) Static Magnetic Field for Dispersing Nucleus AnkyrinG in Human Cultured Glioblastoma Cells
Biomagnetism is one of important biotechnology fields for manipulation of cell lines. However, its peri-cellular level regulation, upon stimulation is not fully developed. Glioblastoma U87 and U251 represent a malignant model in rapid growing cancer. We focused in cellular level dispersion of static magnetic fields (0.2T=2000 ± 600 Gauss), using its fast growing properties. As a result, cytoskeletal protein nuclear Ankyrin G was dispersed. Membrane barriers in TEM microscopy indicated the membranous apparatus change. Our findings bring an insight that static magnetic stimulation creates a specified cytoplasmic intracellular pattern