国际参与者对过去75年热生理学进展的第一手资料即将出版

C. Blatteis
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Their interest was, in part, a continuation of their then still recent wartime experiences when many had served in military laboratories studying the effects of harsh environments on soldiers’ performance. I had the privilege of knowing personally most of the principal players both in the USA and abroad—many sadly now gone—over my 60 years in the field and I recall reasonably well the various steps of our journey of discovery. Right now seemed to me, therefore, an opportune time to recapitulate the history of thermal physiology for the benefit of those among the current generation of workers in all disciplines now involved in our field as well as of others who may be interested in learning about the research that has led to our current knowledge of how the body maintains its temperature. I felt reasonably safe that I could recount with adequate authority and authenticity the American contribution to this history. But my contemporaries in the UK, Germany, Japan, etc. have naturally had closer and more continuous relationships with their own compatriots and, therefore, can reflect on them with greater authority than I. Those that I approached have graciously agreed to be contributors to this history. This book is not meant to be a definitive, exhaustive treatise of the worldwide history of temperature regulation research since its beginning, but rather a personal recounting of, in particular, the people who contributed to its development, told from the memory and subjective perspective of witnesses to it who, moreover, were themselves major participants. 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引用次数: 2

摘要

在过去的60年里,我们对控制体温的机制的理解取得了显著的进步,但除了在教学专著和专题讨论会中偶尔出现的简短的历史背景章节外,据我所知,还没有一本关于热生理学“制造者”的书出版。热生理学是一门综合性的科学,这就是为什么这个领域如此迷人,它的历史如此引人入胜。事实上,当我在1954年作为研究生进入这个领域时,这是一个受各种科学家欢迎的研究领域,包括心血管、呼吸、肌肉骨骼、神经、内分泌和其他生理学家,以及生物化学家、生物物理学家和心理学家,他们都在贡献自己的专业知识,阐明自己的专业在控制体温方面的作用。在某种程度上,他们的兴趣是对战时经历的延续,当时他们中的许多人都曾在军事实验室服役,研究恶劣环境对士兵表现的影响。在我从事这一领域的60年里,我有幸亲自认识了美国和国外的大多数主要参与者——遗憾的是,其中许多人现在已经离开了——我还相当清楚地记得我们探索之旅的各个步骤。因此,对我来说,现在似乎是一个恰当的时机来概括一下热生理学的历史,以造福于现在涉及我们领域的所有学科的当代工作者,以及其他可能有兴趣了解导致我们目前对身体如何保持温度的了解的研究的人。我感到相当安全,我可以以足够的权威和真实性来叙述美国对这段历史的贡献。但我在英国、德国、日本等国家的同代人自然与自己的同胞有着更密切、更持久的关系,因此,他们对同胞的反思比我更有权威。我所接触的那些人都大方地同意为这段历史做出贡献。这本书并不是一本权威的、详尽的关于全球温度调节研究历史的论文,而是一本个人的叙述,特别是对其发展做出贡献的人,从目击者的记忆和主观角度讲述,而且,他们自己也是主要参与者。也就是说,这本书将呈现热生理学的全球历史,而不是作为已经众所周知的,已发表的事实的干涩的重新汇编,而是作为一个生动的叙述,从个人的,几乎是自传的观点受邀贡献者,因此,不仅将被回忆的科学家的重要贡献可能会被突出,而且也因此,一些洞察他们的人格,他们是如何思考和工作的可能会获得。有几个章节已经完成了;它们以独特的风格和作者的个人经验写成(请参见表1)。剩余的章节预计将在今年夏末和初秋出版。该书预计于2015年初出版。它暂定的题目是“热生理学:世界历史”。出版商将是纽约斯普林格出版社。这将是美国生理学会(APS)系列的第八卷,题为“生理学的观点”(以前称为“人与思想”),旨在将医学科学置于更大的历史背景中。国际参与者对过去75年热生理学进展的第一手资料即将出版
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A first-hand account by the international participants of the past 75 years’ advancements in thermophysiology is forthcoming
The past 60 years have witnessed remarkable advances in our understanding of the mechanisms that control body temperature, but except for brief historical background chapters occasionally included in didactic monographs and symposia proceedings, no book, to my best knowledge, has yet been published on the “makers” of thermal physiology. Thermal physiology is an integrative science, and this is what makes the field so fascinating and its history so engrossing. Indeed, when I entered the field as a graduate student in 1954, it was a popular area of research among scientists of all stripes cardiovascular, respiratory, musculo-skeletal, nervous, endocrine and other physiologists as well as biochemists, biophysicists, and psychologists all contributing their expertise toward elucidating the role of their particular specialty in controlling body temperature. Their interest was, in part, a continuation of their then still recent wartime experiences when many had served in military laboratories studying the effects of harsh environments on soldiers’ performance. I had the privilege of knowing personally most of the principal players both in the USA and abroad—many sadly now gone—over my 60 years in the field and I recall reasonably well the various steps of our journey of discovery. Right now seemed to me, therefore, an opportune time to recapitulate the history of thermal physiology for the benefit of those among the current generation of workers in all disciplines now involved in our field as well as of others who may be interested in learning about the research that has led to our current knowledge of how the body maintains its temperature. I felt reasonably safe that I could recount with adequate authority and authenticity the American contribution to this history. But my contemporaries in the UK, Germany, Japan, etc. have naturally had closer and more continuous relationships with their own compatriots and, therefore, can reflect on them with greater authority than I. Those that I approached have graciously agreed to be contributors to this history. This book is not meant to be a definitive, exhaustive treatise of the worldwide history of temperature regulation research since its beginning, but rather a personal recounting of, in particular, the people who contributed to its development, told from the memory and subjective perspective of witnesses to it who, moreover, were themselves major participants. That is to say, this book will present the global history of thermal physiology not as a dry recompilation of already well known, published facts, but rather as a lively account from the personal, almost autobiographical viewpoint of the invited contributors, so that not only the important contributions of the scientists that will be recalled may be highlighted, but also so that some insight into their persona and how they thought and worked may be gained. Several of the chapters are already in; they are written in the unique style and from the personal experience of their authors (please see Table 1). The remaining chapters are expected later this summer and early fall. The expected publication date of the book is early 2015. Its tentative title will be “Thermal Physiology: a worldwide history.” The publisher will be Springer-NY. It will be the 8th volume in the American Physiological Society’s (APS) series titled “Perspectives in Physiology” (formerly “People and Ideas”) “that seeks to place medical science inside a greater historical A first-hand account by the international participants of the past 75 years’ advancements in thermophysiology is forthcoming
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