In Vitro Investigation of Bacterial Cellulose/Turmeric Extract (BC-TE) Nanocomposite for Burn Wound Dressing

: Bacterial cellulose is an interesting polymer material for using as a wound dressing. Bacterial cellulose has an excellent physical and chemical properties such as high biocompatibility, microporosity, transparant, non-toxic, and also it provides moist environment that made this polymer ideal for wound dressing. However, bacterial cellulose itself has no antimicrobial activity to prevent wound infection. To achieve antimicrobial activity, turmeric extract (TE) were impregnated into bacterial cellulose by immersing bacterial cellulose (BC) in turmeric extract solution to produce BC-TE nanocomposite. A scanning electron microscope (SEM) was used to examine the surface morphology of BC and BC–TE nanocomposite. Antimicrobial tests in vitro indicated that BC–TE nanocomposite showed excellent antibacterial activity against Staphylococcus aureus , and Escherichia coli with the inhibition zone of 12.45 mm and 10 mm, respectively