1型糖尿病亚临床甲状腺功能减退患者慢性自身免疫性甲状腺炎结局中的碳水化合物代谢特征

M. S. Mikhina, E. Troshina, T. Nikonova
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摘要

糖尿病和原发性甲状腺功能减退,在慢性自身免疫性甲状腺炎的结果中,内分泌学和执业医生最常见的两种疾病是重要的,不要忘记这些病理可能的关联。这适用于1型和2型糖尿病患者。然而,这两种病理的结合在1型糖尿病中更为常见,这是由于这些疾病的自身免疫性。1型糖尿病患者的临床病例,这是在泵胰岛素治疗的背景下,提出了先前选择的治疗,在过去的2个月,低血糖发作增加。在调查过程中,原发性亚临床甲状腺功能减退症被确定为慢性自身免疫性甲状腺炎的结局。在实现甲状腺功能亢进的背景下,可以在不纠正先前选择的胰岛素治疗的情况下实现碳水化合物代谢的补偿。糖尿病患者甲状腺功能障碍发生率高,其结果是碳水化合物代谢代偿的恶化,因此需要对糖尿病患者的甲状腺功能障碍进行系统的筛查。
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Features of carbohydrate metabolism in a patient with type 1 diabetes mellitus in subclinical hypothyroidism in the outcome of chronic autoimmune thyroiditis
Diabetes mellitus and primary hypothyroidism, in the outcome of chronic autoimmune thyroiditis, the two most common diseases in endocrinology and the practicing doctor are important not to forget about the possible association of these pathologies. This applies to patients with diabetes mellitus, both 1 and 2 types. However, the combination of these two pathologies is more common in type 1 diabetes, which is due to the autoimmune nature of these diseases. A clinical case of a patient with type 1 diabetes mellitus, which is on pump insulin therapy, is presented, which, in the background of previously selected therapy, during the last 2 months, episodes of hypoglycemia increased. In the course of the survey, primary subclinical hypothyroidism was identified, in the outcome of chronic autoimmune thyroiditis. Against the background of the achievement of euthyroidism, it was possible to achieve compensation of carbohydrate metabolism without correction of previously selected insulin therapy. The high incidence of thyroid dysfunction in patients with diabetes mellitus, and as a consequence, the deterioration in the compensation of carbohydrate metabolism, requires a systematic screening of thyroid disorders in the presence of diabetes mellitus.
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