基于机器学习模型的胰腺癌多类别标签分类新方法

Pub Date : 2022-12-22 DOI:10.12694/scpe.v23i4.2019
P. Santosh, M. C. Sekhar
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引用次数: 0

摘要

胰腺癌目前是癌症相关死亡的第四大原因。早期诊断是胰腺癌患者的一个很好的解决方案,可以降低死亡率。由于诊断延迟和缺乏早期预警症状等因素,准确和早期诊断胰腺肿瘤是一项艰巨的任务。传统的分布式机器学习技术如支持向量机和逻辑回归在降低错误率和提高胰腺癌分类精度方面效果不佳。为此,本文提出了分布式杂交精英基因二次判别强化学习分类器系统(DHEGQDRLCS)。首先,从存储库数据集收集数据样本的数量。此资料库包含胰腺癌预后生物标记物鉴定所需的所有文件。数据收集完成后,进行训练样本和测试样本的分离,实现胰腺癌样本的准确分类。然后将训练样本应用到分布式混合精英基因二次判别强化学习分类器系统中。提出的混合分类器系统采用核二次判别函数对训练样本进行分析。然后应用精英梯度基因优化将样本分为非癌性胰腺、良性肝胆疾病即胰腺癌、胰腺导管腺癌等多个类别。然后基于目标分类结果和预测分类结果,应用强化学习技术最小化损失函数。最后,杂交方法提高了胰腺癌的诊断准确性。采用Hadoop分布式系统对胰腺癌数据集进行实验评估,采用准确度、平衡准确度、F1-score、精密度、召回率、特异性、TN、TP、FN、FP、ROC_AUC、PRC_AUC、PRC_APS等不同的定量指标。性能分析结果表明,与现有方法相比,DHEGQDRLCS具有更高的诊断准确率。
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An Efficient Novel Approach with Multi Class Label Classification through Machine Learning Models for Pancreatic Cancer
Pancreatic cancer is right now the fourth largest cause of cancer-related deaths. Early diagnosis is one good solution for pancreatic cancer patients and reduces the mortality rate. Accurate and earlier diagnosis of the pancreatic tumor is a demanding task due to several factors such as delayed diagnosis and absence of early warning symptoms. The conventional distributed machine learning techniques such as SVM and logistic regression were not efficient to minimize the error rate and improve the classification of pancreatic cancer with higher accuracy. Therefore, a novel technique called Distributed Hybrid Elitism gene Quadratic discriminant Reinforced Learning Classifier System (DHEGQDRLCS) is developed in this paper. First, the number of data samples is collected from the repository dataset. This repository contains all the necessary files for the identification of prognostic biomarkers for pancreatic cancer. After the data collection, the separation of training and testing samples is performed for the accurate classification of pancreatic cancer samples. Then the training samples are considered and applied to Distributed Hybrid Elitism gene Quadratic discriminant Reinforced Learning Classifier System. The proposed hybrid classifier system uses the Kernel Quadratic Discriminant Function to analyze the training samples. After that, the Elitism gradient gene optimization is applied for classifying the samples into multiple classes such as non-cancerous pancreas, benign hepatobiliary disease i.e., pancreatic cancer, and Pancreatic ductal adenocarcinoma. Then the Reinforced Learning technique is applied to minimize the loss function based on target classification results and predicted classification results. Finally, the hybridized approach improves pancreatic cancer diagnosing accuracy. Experimental evaluation is carried out with pancreatic cancer dataset with Hadoop distributed system and different quantitative metrics such as Accuracy, balanced accuracy, F1-score, precision, recall, specificity, TN, TP, FN, FP, ROC_AUC, PRC_AUC, and PRC_APS. The performance analysis results indicate that the DHEGQDRLCS provides better diagnosing accuracy when compared to existing methods.
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