氧化银纳米粒子辅助激光解吸/电离质谱法检测低分子量化合物。

Q3 Physics and Astronomy Mass spectrometry Pub Date : 2014-04-01 DOI:10.5702/massspectrometry.S0025
S. Taira, H. Taguchi, Reiko Fukuda, Kohei Uematsu, Y. Ichiyanagi, Yukie Tanaka, Yutaka Fujii, H. Katano
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引用次数: 7

摘要

基于氧化银纳米颗粒的特定性质允许分析物电离,从而产生智能分析方法的各种应用。纳米颗粒(d=6.7 nm)含有Ag2O核。通过使用氧化银纳米颗粒来检测几种模型化合物(一种核碱基和两种头发生长促进剂)。靶分子与银的两种稳定同位素(Ag(107)和Ag(109))之间产生加合物,形成特异性信号和质子化信号。因此,可以很容易地确定给定的信号是否与目标分子相关。
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Silver Oxide Based Nanoparticle Assisted Laser Desorption/Ionization Mass Spectrometry for the Detection of Low Molecular Weight Compounds.
A specific property of silver oxide-based nanoparticles permits the ionization of an analyte, giving rise to various applications of a smart analytical methodology. The nanoparticles (d=6.7 nm) contained an Ag2O core. The detection of several model componds (a nucleobase and two hair growth promoters) via the use of silver oxide nanoparticles is described. Adducts were produced between the target molecules and the two silver stable isotopes (Ag(107) and Ag(109)), resulting in the formation of specific signals as well as a protonated signal. Thus, it was possible to easily determine whether the given signals were correlated with the target molecule or not.
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来源期刊
Mass spectrometry
Mass spectrometry Physics and Astronomy-Instrumentation
CiteScore
1.90
自引率
0.00%
发文量
3
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