基于语言分析的Nasalance评分差异与COVID-19早期传播的可能关联

Kong-Geun Lee, S. Shim, Jae Heon Kim
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摘要

2020年3月11日,在114个国家报告了超过11.8万例2019冠状病毒病(COVID-19)病例后,世界卫生组织(世卫组织)宣布全球大流行。我们的研究根据世卫组织数据分析了从第一位确诊患者开始直至传播高峰的累积发病率。此外,对正常受试者的鼻测量值进行量化,分析其语言特征。方法:本研究包括两种主要方法,一种是基于正常成人鼻测量数据的荟萃分析,另一种是基于世卫组织数据的累积发病率。此外,对正常受试者的鼻测量值进行量化,分析其语言特征。结果:语族间口语文本鼻音平衡的总平均差异(MDs)为阿拉伯语14.655(95%可信区间[CI], 7.986-21.324),汉语24.441 (95% CI, 17.920-30.962),欧洲语系14.964 (95% CI, 13.677-16.251),乌拉尔-阿尔泰语系11.437 (95% CI, 9.88 - 12.994)。COVID-19累积发病率的总MDs在阿拉伯地区为190.3 (95% CI, 56.10-324.60),欧洲地区为283.20 (95% CI, 1.80-564.60),乌拉尔-阿尔泰地区为5.70 (95% CI, 4.90-6.60)。口腔鼻翼平衡评分与累计发病率有显著相关性(P=0.0004)。结论:我们的研究显示语言特征与COVID-19的早期传播可能存在关联。需要进一步的研究来验证我们基于各种流行病学和行为因素(包括戴口罩)的结果。
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Possible Association between Differences in Nasalance Scores and Early Spread of COVID-19 Based on Linguistic Analysis
Objective: The World Health Organization (WHO) declared a pandemic on March 11, 2020 after more than 118,000 cases of coronavirus disease 2019 (COVID-19) had been reported in 114 countries. Our study analyzed the cumulative incidence rate based on WHO data starting with the first confirmed patient until the peak of transmission. In addition, the numerical values of nasometry from normal subjects were quantified to analyze the linguistic features.Methods: This study consisted of two main methodologies including a meta-analysis based on nasometry data involving normal adults and cumulative incidence rate based on WHO data. In addition, the numerical values of nasometry from normal subjects were quantified to analyze the linguistic features.Results: The pooled overall mean differences (MDs) for oral text nasalance among linguistic families were 14.655 (95% confidence interval [CI], 7.986–21.324) in Arabic, 24.441 (95% CI, 17.920–30.962) in Chinese, 14.964 (95% CI, 13.677–16.251) in European, and 11.437 (95% CI, 9.880–12.994) in Ural-Altaic. The pooled overall MDs for cumulative incidence rate of COVID-19 were 190.3 (95% CI, 56.10–324.60) in Arabic, 283.20 (95% CI, 1.80–564.60) in European, and 5.70 (95% CI, 4.90–6.60) in Ural-Altaic. Correlation between oral nasalance score and cumulative incidence was significant (P=0.0004).Conclusion: Our study showed the possible association between language characteristics and early spread of COVID-19. Further studies are needed to validate our outcomes based on various epidemiologic and behavioral factors including mask wearing.
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