脑动脉瘤的个性化数学建模

A. Khe, A. Chupakhin, A. Cherevko, D. Parshin, A. Krivoshapkin, K. Orlov
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引用次数: 1

摘要

在这项工作中,我们描述了一个数学和计算框架,用于在存在动脉瘤的情况下进行脑血流动力学的个性化建模。作为一个例子,我们研究了脑动脉瘤的非局部流体力学性质。通过数值模拟确定了动脉瘤对周围血流的影响范围,以及压力升高和降低所引起的血流变化,并研究了多发动脉瘤时的血流特征。对于我们的计算,我们使用术中血管内测量获得的个性化临床数据。
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Personalized mathematical modeling of cerebral arterial aneurysms
In this work we describe a mathematical and computational framework for personalized modeling of the cerebral hemodynamics in the presence of arterial aneurysms. As an example we study nonlocal hydrodynamic properties of cerebral arterial aneurysms. Using numerical simulations we determine the area of influence of the aneurysm on the surrounding blood flow, the changes induced by increase and decrease of the pressure, and we study the flow features in the case of multiple aneurysms. For our computations we use personalized clinical data obtained during intraoperative endovascular measurements.
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