血液透析患者一例可能的少动鞘膜单胞菌心内膜炎

P. Samarakoon, K. Bandara, A. Pathirana, T. Matthias, N. Chandrasiri
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引用次数: 0

摘要

少动鞘氨单胞菌广泛分布于环境中,偶尔引起人类感染,最常发生在免疫功能低下的个体中。罕见的侵袭性和严重感染的报道包括脓毒性关节炎,骨髓炎,囊性纤维化患者的呼吸道感染和坏死性软组织感染。在国际文献中,心内膜炎的病例报道很少。斯里兰卡没有公布的病例。我们描述一个可能的少动鞘单胞菌心内膜炎病例。一位58岁男性患者在血液透析后表现为反应性降低。入院时进行的三次血培养均为少动鞘单胞菌阳性。他的超声心动图不能排除心内膜炎。他接受了适当的抗生素治疗,但不幸因吸入性肺炎后感染性休克而死亡。本病例表明,低毒力的微生物可引起终末期肾脏疾病患者的心内膜炎。这也表明与免疫正常的患者相比,这类患者相对无症状或症状较少。
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A possible Sphingomonas paucimobilis endocarditis in a haemodialysed patient: A case report
Sphingomonas paucimobilis is widely distributed in the environment and causes occasional human infections, most often in immunocompromised individuals. Reports of unusual invasive and severe infections include septic arthritis, osteomyelitis, respiratory tract infections in patients with cystic fibrosis and necrotising soft tissue infections. There are only few reported cases of endocarditis in the international literature. There are no published cases in Sri Lanka.We describe a possible case of Sphingomonas paucimobilis endocarditis. A 58 year old male patient presented with reduced responsiveness following haemodialysis. All three blood cultures taken on admission were positive for Sphingomonas paucimobilis. His echocardiography could not exclude endocarditis. He was treated with appropriate antibiotics but unfortunately expired due to septic shock following aspiration pneumonia. This case demonstrates that organisms of low virulence could cause endocarditis in patients with end stage renal disease. It also indicates that such patients are relatively asymptomatic or have few symptoms compared to patients with normal immunity.
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