重金属中毒和肿瘤——可能的关联

Lucia Bubulac, Dan Octavian Marculescu, V. Purcarea
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引用次数: 1

摘要

作为工业化的副作用,一些疾病是最近才发展起来的,这对医学专家在研究和医疗领域都是一个挑战。其中,重金属中毒是必须引起重视的一类,因为如果不正确认识和治疗,这种中毒的影响是非常严重的。与中毒有关的最常见重金属是汞、镉、铅和砷。它们能够诱发广泛的病理,包括脑局限性肿瘤。为了说明重金属中毒与肿瘤之间的联系,我们提出了一个19岁患者的病例,他被诊断为生殖细胞瘤,这是一种恶性肿瘤的正中脑结构,和汞中毒。由于生殖细胞瘤和汞中毒是罕见的情况,很难获得足够的数据进行统计上有意义的研究。然而,包括重金属中毒和生殖细胞瘤的案例研究支持了在被诊断为汞中毒的个人进行适当筛查的想法,特别是当他们可能被证明是可以治疗的时候。关键词:中毒,汞中毒,生殖细胞瘤,脑肿瘤,脑肿瘤。
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Poisonings with heavy metals and neoplasms - possible correlations
As a side effect of industrialization, some diseases have developed only recently, becoming a challenge for the medical specialists both in research and medical treatment fields. Among these, the poisoning with heavy metals occupies a certain category that must retain attention, due to since the effects of this kind of poisoning are very serious effects if these injuries poisonings are not properly recognized and treated. Most common heavy metals that are involved in poisonings are Mercury, Cadmium, Lead and Arsenic. They are capable of inducing a wide range of pathologies, including neoplasms with cerebral localization. In order to illustrate the link between the poisonings with heavy metals and neoplasms, we present a case of a 19 years old patient, who was diagnosed both with germinoma, which is a malignant tumor of the median brain structures, and mercury poisoning. Since germinoma and mercury poisoning are rare conditions, it is very hard to obtain enough data for a statistically significant study. However, the case study which encompasses the poisoning with heavy metals and germinoma supports the idea of performing proper screenings in the event of individuals being diagnosed with mercury poisoning, especially when they can turn out to be potentially treatable.  Key words: Poisoning, mercury poisoning, germinoma, cerebral tumor, cerebral neoplasm.
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