{"title":"仿生抗菌传感丝生物贴片","authors":"Zhiheng Gao, T. Tao, Keyin Liu","doi":"10.1109/Transducers50396.2021.9495518","DOIUrl":null,"url":null,"abstract":"We report a class of biomimic silk-based bio-patches with inherent bacterial inhibition and infection monitoring function. Mechanical properties of the silk bio-patch can be well-tuned to match the elastic modulus of human patches such as dura mater and hernia patch. The silk bio-patch can be functionalized by facilely adding bioactive drugs and bio-factors. Bacterial inhibition can be achieved by the micro-patterns of the optical diffraction element (DOE) on the silk bio-patch. Besides, the DOE in the silk bio-patch can be used to monitor tissue infection by detecting the change of the diffraction pattern. Our approach offers potential to developing multifunctional implantable devices in biomedical applications.","PeriodicalId":6814,"journal":{"name":"2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)","volume":"42 1","pages":"1420-1423"},"PeriodicalIF":0.0000,"publicationDate":"2021-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Biomimic Antibacterial Sensing Silk Bio-Patch\",\"authors\":\"Zhiheng Gao, T. Tao, Keyin Liu\",\"doi\":\"10.1109/Transducers50396.2021.9495518\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We report a class of biomimic silk-based bio-patches with inherent bacterial inhibition and infection monitoring function. Mechanical properties of the silk bio-patch can be well-tuned to match the elastic modulus of human patches such as dura mater and hernia patch. The silk bio-patch can be functionalized by facilely adding bioactive drugs and bio-factors. Bacterial inhibition can be achieved by the micro-patterns of the optical diffraction element (DOE) on the silk bio-patch. Besides, the DOE in the silk bio-patch can be used to monitor tissue infection by detecting the change of the diffraction pattern. Our approach offers potential to developing multifunctional implantable devices in biomedical applications.\",\"PeriodicalId\":6814,\"journal\":{\"name\":\"2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)\",\"volume\":\"42 1\",\"pages\":\"1420-1423\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-06-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/Transducers50396.2021.9495518\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/Transducers50396.2021.9495518","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
We report a class of biomimic silk-based bio-patches with inherent bacterial inhibition and infection monitoring function. Mechanical properties of the silk bio-patch can be well-tuned to match the elastic modulus of human patches such as dura mater and hernia patch. The silk bio-patch can be functionalized by facilely adding bioactive drugs and bio-factors. Bacterial inhibition can be achieved by the micro-patterns of the optical diffraction element (DOE) on the silk bio-patch. Besides, the DOE in the silk bio-patch can be used to monitor tissue infection by detecting the change of the diffraction pattern. Our approach offers potential to developing multifunctional implantable devices in biomedical applications.
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