口咽吞咽困难伴误吸是COPD加重的诱发因素

Noor Sameh Darwich, Shamsuddin Chowdhry Pracha, Natalie Ann Miller
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摘要

慢性阻塞性肺疾病(COPD)恶化最常见的诱发因素包括病毒性和细菌性气管支气管炎、肺炎以及暴露于环境刺激物和空气污染。在许多COPD加重患者中,根本原因无法确定。一般来说,慢性阻塞性肺病加重患者会被送进医院,接受抗生素、糖皮质激素和吸入支气管扩张剂治疗。口咽吞咽困难是COPD恶化的一个未被充分认识的诱发因素。晚期慢性阻塞性肺病患者通常呼吸和吞咽协调能力受损,这可能导致液体、食物颗粒和唾液吸入气道。吸入性事件可导致症状加重并导致肺功能进一步下降。我们描述了一位69岁男性,有慢性阻塞性肺病病史,表现为进行性呼吸困难,生产性咳嗽和缺氧,需要插管和机械通气。患者行支气管镜检查,发现右侧主支气管有肉块被切除。据报告,病人在入院前吞咽固体食物有困难。
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Oropharyngeal Dysphagia with Aspiration as a Provoking Factor for COPD Exacerbation
The most common provoking factors for chronic Obstructive Pulmonary Disease (COPD) exacerbation include viral and bacterial tracheobronchitis, pneumonia, and exposure to environmental irritants and air pollution. In many patients with COPD exacerbation, the underlying cause cannot be identified. In general, patients with COPD exacerbation get admitted to the hospital and treated with antibiotics, glucocorticoids and inhaled bronchodilators. Oropharyngeal dysphagia is an under-recognized provoking factor for COPD exacerbation. Patients with advanced COPD often have impaired coordination of respiration and deglutition which can lead to aspiration of liquids, food particles, and saliva into the airways. Aspiration events can lead to exacerbation of symptoms and cause further decline in lung function. We described a 69-year-old male with a history of COPD who presented with progressive dyspnea, productive cough and hypoxia which required intubation and mechanical ventilation. The patient underwent a bronchoscopy for airway inspection which showed pieces of meat in the right main bronchus which were removed. Reportedly, the patient was having difficulty swallowing solid food prior to admission to the hospital.
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