一些生化变异与肝炎患者的关系

A. M. Aljebory
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摘要

肝炎是一种病毒性疾病;它在不同国家的人群中分布广泛,有五种以上的常见类型;A、B、C、D、E.测定19 ~ 50岁男女慢性乙型和丙型肝炎患者血清总蛋白、白蛋白和铁蛋白水平;同时,在表面正常的健康志愿者中也测量了相同的方差。有其他肝脏疾病的患者被排除在本研究之外。正常志愿者的总蛋白、白蛋白和铁蛋白的平均值男性分别为5.33、4.742和51.458 g/ dl,女性为5.342、4.733和51.667 g/ dl。男性为3.399、2.878、77.909 g/dl,女性为3.429、3.092、137.091g/dl。而在HCV中,男性总蛋白、白蛋白和铁蛋白分别为4.045、3.462和151.182 g/dl,女性分别为3.838、3.391和68.167 g/dl。统计分析结果显示,B、c两例患者与对照组相比,各方差值均有显著性意义。其中,HBV男性患者总蛋白、白蛋白和铁蛋白的p值分别为6.41 e -19、5.11E-17和1.96E-12,女性患者的p值分别为1.6E-18、2.03E-15和3.65E-24。HCV型男性患者总蛋白、白蛋白和铁蛋白的p值分别为8.01E-10、1.9E-10和5.13E-17,女性患者的p值分别为1.79E-16、3.36E-12和1.78E-05。结果还表明,两种类型患者的所有方差之间存在正相关。
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Relatioship of Some Biochemical Variance with Hepatitis Patients
Hepatitis is a viral disease; it has a wide distribution among peoples in different countries' and it has more than five common types named; A, B, C, D and E. The serum level of total protein, albumin and ferritin was estimated in patients with chronic hepatitis B and C, in male and female aged from 19 – 50 years; at the same time same variance was measured in apparently normal healthy volunteers. A patient with other liver disease was excluded from this search. The average values for total protein, albumin, and ferritin for normal volunteers are (5.33, 4.742 and 51.458 g/ dl) respectively for male and 5.342, 4.733 and 51.667 g/ dl in the female. While its value in HBV was (3.399, 2.878 and 77.909 g/dl) for male and 3.429, 3.092 and 137.091g/dl in female respectively. While in HCV, the value for total protein, albumin and ferritin was (4.045, 3.462 and 151.182 g/dl) respectively in male and 3.838, 3.391 and 68.167 respectively in the female. Using statistical analysis, the results indicate that there is a significant value for all variances when compared with the control in both cases B and C. The p-value was highly significant its value in HBV male patients is 6.4E-19, 5.11E-17 and 1.96E-12 for total protein, albumin and ferritin respectively and 1.6E-18, 2.03E-15 and 3.65E-24 for female. While in type HCV male patients the pvalues were 8.01E-10, 1.9E-10 and 5.13E-17 for total protein, albumin and ferritin respectively, in female the values are 1.79E-16, 3.36E-12 and 1.78E-05 respectively. The results indicate also a positive correlation between all of the variance in the two types of patients.
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