尼日利亚贝宁市贝宁大学教学医院蛇咬伤发生率及抗蛇毒血清的使用

S. Aghahowa, R. N. Ogbevoen
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引用次数: 3

摘要

背景:动物咬伤似乎是一种被忽视的疾病。由于我院有急诊报告病例,有必要对其发生率和用药情况进行评估。目的:了解尼日利亚贝宁市贝宁大学教学医院急诊中心12年来蛇咬伤发生率及抗蛇毒血清的使用情况。材料与方法:在获得许可后,从该中心收集2000 - 2011年蛇咬伤病历和抗蛇毒血清使用数据进行评估。结果:129例蛇咬伤患者共使用多价抗蛇毒血清136瓶。其中男性103例(79.9%),女性26例(20.2%),年龄在2岁至68岁之间(中位34岁)。发病率在29 - 36岁的年轻成年男性中明显较高。四肢是最常见的咬伤部位,农民是最易被咬伤的部位,占非技术工人75人(58.14%)的比例较大。到达医院时,90例(69.8%)患者在被咬部位上方使用局部止血带。他们对蛇的唯一描述就是颜色和大小。34例患者在到医院报到前先看了中医。口服喹诺酮(环丙沙星)和双氯芬酸是最常用的抗菌和抗炎药物。最长住院时间为(102±0.61 h),治疗期间无毒蛇中毒死亡和药物不良反应。结论:强烈建议在药品采购过程中储备足够的抗蛇毒血清,因为如果不及时治疗,蛇咬伤并发症可能致命。
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Incidence of snake bite and utilization of antivenom in the University of Benin Teaching Hospital Benin City, Nigeria
Background: Bite resulting from animals seems to be a neglected disease. Since there were cases reported as emergency our institution, there is need to assess the incidence and drug utilization. Objective: To assess the incidence of snake bite and utilization of antivenom over 12 years in the Accident and Emergency Centre of the University of Benin Teaching Hospital, Benin City, Nigeria. Materials and Methods: Data from medical record of snake bite and antivenom utilization between the year 2000 and 2011 were assessed from the centre after obtaining permission. Results: One hundred and thirty-six vials of polyvalent antivenom were utilized in the management of 129 patients that reported with snake bite. The victims were 103 (79.9%) males and 26 (20.2%) females within range of 2 years to 68 years (median, 34 years). The incidence was significantly higher among young adult males aged between 29 and 36 years. Limbs were the most common sites of bite and farmers were the most vulnerable which constituted larger proportion of 75 (58.14%) of unskilled workers. On arrival at the hospital, 90 (69.8%) of the victims had local tourniquet applied above the bitten sites. Their only description of snake was in color and size. Thirty-four patients visited herbalist before reporting to hospital. Oral quinolone (ciprofloxacin) and diclofenac were the most frequently used antibacterial and anti-inflammatory agents. Maximum duration of hospitalization was (102 ± 0.61 h). No death was recorded following snake envenomation and no adverse drug reaction during therapy. Conclusion: Adequate stocking of antivenom is strongly recommended during drug procurement because snake bite complications can be fatal if not promptly treated.
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