骨支架设计概念与设计方法综述

IF 10.1 2区 工程技术 Q1 ENGINEERING, MECHANICAL Facta Universitatis-Series Mechanical Engineering Pub Date : 2023-04-10 DOI:10.22190/fume200328038m
J. Milovanovic, M. Stojković, M. Trifunovic, N. Vitković
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引用次数: 2

摘要

本文提出了现有的,最先进的方法来设计用于组织工程的支架的几何结构,特别强调了用于骨组织恢复的宏观支架。不同作者的相似概念被组织成组。本文的重点是确定现有的概念以及它们的优缺点。除了对支架几何方案的回顾之外,对现有设计的分析指出了一些关于支架在(骨)组织恢复中的作用的严重误解。在论文的最后一节,重新考虑了几何结构的主要要求,即结构和相应的力学性能和渗透率。
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REVIEW OF BONE SCAFFOLD DESIGN CONCEPTS AND DESIGN METHODS
The paper brings out a review of existing, state-of-the-art approaches to designing the geometry of the scaffolds that are used for tissue engineering with a special emphasis on the macro scaffolds aimed for bone tissue recovery. Similar concepts of different authors are organized into groups. The focus of the paper is on determining the existing concepts as well as their advantages and disadvantages. Besides the review of scaffolds' geometry solutions, the analysis of the existing designs points to some serious misconceptions regarding the scaffold role within the (bone) tissue recovery. In the last section of the paper, the main requirements regarding geometry, that is, architecture and corresponding mechanical properties and permeability are reconsidered.
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来源期刊
CiteScore
14.40
自引率
2.50%
发文量
12
审稿时长
6 weeks
期刊介绍: Facta Universitatis, Series: Mechanical Engineering (FU Mech Eng) is an open-access, peer-reviewed international journal published by the University of Niš in the Republic of Serbia. It publishes high-quality, refereed papers three times a year, encompassing original theoretical and/or practice-oriented research as well as extended versions of previously published conference papers. The journal's scope covers the entire spectrum of Mechanical Engineering. Papers undergo rigorous peer review to ensure originality, relevance, and readability, maintaining high publication standards while offering a timely, comprehensive, and balanced review process.
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