绿色合成的硫原和硫属化物纳米颗粒在癌症治疗中的新作用

IF 3.9 Q2 NANOSCIENCE & NANOTECHNOLOGY Journal of Nanotechnology Pub Date : 2022-05-12 DOI:10.1155/2022/6176610
F. Olawale, O. Oladimeji, M. Ariatti, Moganavelli Singh
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引用次数: 8

摘要

在过去的几十年里,无机纳米颗粒的研究数量有了压倒性的增长。更令人着迷的是在癌症治疗中使用硫元和硫属纳米粒子取得的巨大进展。这些纳米材料最初是通过化学方法合成的,现在已经用不同的植物材料有效地生产出来。纳米粒子合成的生物途径的范式转变源于其生物安全、生态友好和简单等优越优势。尽管通过绿色化学合成无机纳米粒子已有大量的综述,但目前关于用于癌症研究的硫原和硫属化合物的绿色合成的信息缺乏。含有硫、硒和碲等硫原及其硫属化合物的纳米制剂最近成为癌症治疗和诊断的有前途的工具。与其他无机纳米颗粒类似,硫原和硫属化合物是利用植物提取物及其纯化的生物分子合成的。本文综述了植物介导的硫原和硫属化合物合成的最新进展,并重点介绍了它们在癌症治疗中的应用。
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Emerging Roles of Green-Synthesized Chalcogen and Chalcogenide Nanoparticles in Cancer Theranostics
The last few decades have seen an overwhelming increase in the amount of research carried out on the use of inorganic nanoparticles. More fascinating is the tremendous progress made in the use of chalcogen and chalcogenide nanoparticles in cancer theranostics. These nanomaterials, which were initially synthesized through chemical methods, have now been efficiently produced using different plant materials. The paradigm shift towards the biogenic route of nanoparticle synthesis stems from its superior advantages of biosafety, eco-friendliness, and simplicity, among others. Despite a large number of reviews available on inorganic nanoparticle synthesis through green chemistry, there is currently a dearth of information on the green synthesis of chalcogens and chalcogenides for cancer research. Nanoformulations involving chalcogens such as sulfur, selenium, and tellurium and their respective chalcogenides have recently emerged as promising tools in cancer therapeutics and diagnosis. Similar to other inorganic nanoparticles, chalcogens and chalcogenides have been synthesized using plant extracts and their purified biomolecules. In this review, we provide an up-to-date discussion of the recent progress that has been made in the plant-mediated synthesis of chalcogens and chalcogenides with a special focus on their application in cancer theranostics.
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来源期刊
Journal of Nanotechnology
Journal of Nanotechnology NANOSCIENCE & NANOTECHNOLOGY-
CiteScore
5.50
自引率
2.40%
发文量
25
审稿时长
13 weeks
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