{"title":"纳米材料作为检测和对抗病毒的诊断工具","authors":"Rama Sharma","doi":"10.2174/2210681213666230428112658","DOIUrl":null,"url":null,"abstract":"\n\nThe primary cause of death worldwide is an infectious disease, and viruses in particular, have a\nmajor worldwide impact on health and economic growth. A critical public health problem is the quick\nemergence of medication resistance to currently accessible treatments as well as negative side effects\nfrom repeated use. Therefore, the creation of novel treatment plans is necessary. In contrast to\nconventional chemical-based antiviral drugs, the use of nanoparticles offers an alluring potential for the\ndevelopment of innovative antiviral therapies with minimal risk of acquiring drug resistance.\nNanomaterials make it simple to change the properties of accessible resources. Nanomaterials can be\nreadily applied to modify the available detection platforms to improve their sensitivity. Due to their high\nsurface-to-volume ratio, NPs readily bind to either the viral membrane proteins or the viral reproduction\nsystem (DNA/RNA), thus hindering the virus' ability to infect cells. Viral proliferation has been inhibited\nby the use of metal nanoparticles (NPs) such as gold, silver, and copper. Copper has repeatedly been examined for its strong anti-microbial qualities due to its lower cost than silver and gold. The virus's inactivation on copper surfaces after 4 hours raises the possibility that copper could be used to destroy the infection. Also, it was discovered that 50% of virus-like particles (VLPs) could be rendered inactive by\ncopper composite nanoparticles in just 10 minutes. The medical community could benefit greatly from\nsophisticated smartphone and/or LFA-based detection techniques that can be used right at the patient's\nbedside. This review discusses methods based on nanotechnology for diagnosing and treating viral\ndiseases, especially HIV and influenza.\n","PeriodicalId":38913,"journal":{"name":"Nanoscience and Nanotechnology - Asia","volume":"39 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Nanomaterials As Theragnostic Tools of Detection and Fighting off the Virus\",\"authors\":\"Rama Sharma\",\"doi\":\"10.2174/2210681213666230428112658\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n\\nThe primary cause of death worldwide is an infectious disease, and viruses in particular, have a\\nmajor worldwide impact on health and economic growth. A critical public health problem is the quick\\nemergence of medication resistance to currently accessible treatments as well as negative side effects\\nfrom repeated use. Therefore, the creation of novel treatment plans is necessary. In contrast to\\nconventional chemical-based antiviral drugs, the use of nanoparticles offers an alluring potential for the\\ndevelopment of innovative antiviral therapies with minimal risk of acquiring drug resistance.\\nNanomaterials make it simple to change the properties of accessible resources. Nanomaterials can be\\nreadily applied to modify the available detection platforms to improve their sensitivity. Due to their high\\nsurface-to-volume ratio, NPs readily bind to either the viral membrane proteins or the viral reproduction\\nsystem (DNA/RNA), thus hindering the virus' ability to infect cells. Viral proliferation has been inhibited\\nby the use of metal nanoparticles (NPs) such as gold, silver, and copper. Copper has repeatedly been examined for its strong anti-microbial qualities due to its lower cost than silver and gold. The virus's inactivation on copper surfaces after 4 hours raises the possibility that copper could be used to destroy the infection. Also, it was discovered that 50% of virus-like particles (VLPs) could be rendered inactive by\\ncopper composite nanoparticles in just 10 minutes. The medical community could benefit greatly from\\nsophisticated smartphone and/or LFA-based detection techniques that can be used right at the patient's\\nbedside. This review discusses methods based on nanotechnology for diagnosing and treating viral\\ndiseases, especially HIV and influenza.\\n\",\"PeriodicalId\":38913,\"journal\":{\"name\":\"Nanoscience and Nanotechnology - Asia\",\"volume\":\"39 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-04-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nanoscience and Nanotechnology - Asia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/2210681213666230428112658\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Engineering\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nanoscience and Nanotechnology - Asia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/2210681213666230428112658","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Engineering","Score":null,"Total":0}
Nanomaterials As Theragnostic Tools of Detection and Fighting off the Virus
The primary cause of death worldwide is an infectious disease, and viruses in particular, have a
major worldwide impact on health and economic growth. A critical public health problem is the quick
emergence of medication resistance to currently accessible treatments as well as negative side effects
from repeated use. Therefore, the creation of novel treatment plans is necessary. In contrast to
conventional chemical-based antiviral drugs, the use of nanoparticles offers an alluring potential for the
development of innovative antiviral therapies with minimal risk of acquiring drug resistance.
Nanomaterials make it simple to change the properties of accessible resources. Nanomaterials can be
readily applied to modify the available detection platforms to improve their sensitivity. Due to their high
surface-to-volume ratio, NPs readily bind to either the viral membrane proteins or the viral reproduction
system (DNA/RNA), thus hindering the virus' ability to infect cells. Viral proliferation has been inhibited
by the use of metal nanoparticles (NPs) such as gold, silver, and copper. Copper has repeatedly been examined for its strong anti-microbial qualities due to its lower cost than silver and gold. The virus's inactivation on copper surfaces after 4 hours raises the possibility that copper could be used to destroy the infection. Also, it was discovered that 50% of virus-like particles (VLPs) could be rendered inactive by
copper composite nanoparticles in just 10 minutes. The medical community could benefit greatly from
sophisticated smartphone and/or LFA-based detection techniques that can be used right at the patient's
bedside. This review discusses methods based on nanotechnology for diagnosing and treating viral
diseases, especially HIV and influenza.
期刊介绍:
Nanoscience & Nanotechnology-Asia publishes expert reviews, original research articles, letters and guest edited issues on all the most recent advances in nanoscience and nanotechnology with an emphasis on research in Asia and Japan. All aspects of the field are represented including chemistry, physics, materials science, biology and engineering mainly covering the following; synthesis, characterization, assembly, theory, and simulation of nanostructures (nanomaterials and assemblies, nanodevices, nano-bubbles, nano-droplets, nanofluidics, and self-assembled structures), nanofabrication, nanobiotechnology, nanomedicine and methods and tools for nanoscience and nanotechnology.