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The evidence that steam was a waste of time was well established even by this time—plus the risks of directly or indirectly teaching parents insanities like ‘boil a kettle in the corner of the child’s room’ were apparent. But it took a practical issue like fire alarms to make us change our practice. I recalled this experience when reading the paper from Carroll and Sinivas (see page 113). They describe the very familiar scenario of a 13-month-old child with recurrent wheeze; indeed they comment that they’ve seen dozens of such patients in the last 12 months. It made me think that if they’d only so few, then no wonder they’ve the time to write such an excellent review; sometimes it seems that my practice is wall to wall with such patients. We’ve got used to using our slightly more modern ‘toil and trouble’ treatments —because, boy, nebulisers are jolly efficacious looking treatments, aren’t they? Indeed, if you compared a nebuliser with, say, a bone marrow transplant—perhaps the single most anticlimactic looking therapy I’ve ever observed—then I know which one looks the more efficacious. But in this careful review they note that there really is no evidence that bronchodilators are of any use in the vast majority of patients, and that our—and our families’—perception that they’re helpful is just that. This paper is this month’s Editor’s choice. So, speaking of perceptions of usefulness, who has bought into the sales pitch for the newer tests for TB—the interferon γ release assays (IGRA) tests? I’ll admit that I did, buoyed up by enthusiasm from a number of sources. A shame then that they’re a tricky and expensive way of saying pretty much exactly the same as a Mantoux—with roughly the same specificity and sensitivity. 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引用次数: 0

摘要

当我还是一名新儿科医生时,我在一个常规使用蒸汽治疗患有哮喘病的儿童的单位工作。这是一种奇妙的治疗方法——你可以感觉到你正在做一些非常有效的事情;你会打开小隔间的门查看一下孩子,然后走进这种潮湿的气氛——你几乎可以听到女巫们在高喊“加倍,加倍的辛劳和烦恼;火在燃烧,大锅在远处冒泡。只有一个问题。简直是垃圾。当我们安装了新的烟雾探测器系统时,这一点得到了充分的证明,该系统是由蒸汽触发的,因此我们不得不停止使用它;这对我们治疗的孩子完全没有影响。蒸汽是浪费时间的证据,即使在那个时候也已经得到了充分的证明,而且直接或间接地教导父母“在孩子房间的角落烧壶”这样的疯狂行为的风险是显而易见的。但是像火警这样的实际问题让我们改变了我们的做法。当我读到Carroll和Sinivas的论文(见第113页)时,我想起了这段经历。他们描述了一个非常熟悉的13个月大的孩子反复喘息的场景;事实上,他们评论说,在过去的12个月里,他们已经见过几十个这样的病人。这让我想到,如果他们只有这么几个,难怪他们有时间写这么好的评论;有时候,我的诊所里似乎挤满了这样的病人。我们已经习惯了使用稍微现代一点的“辛劳和麻烦”的治疗方法——因为,天哪,喷雾器看起来是非常有效的治疗方法,不是吗?事实上,如果你把喷雾器和骨髓移植——也许是我所见过的最令人扫兴的疗法——进行比较,我就知道哪一种看起来更有效。但在仔细的回顾中,他们注意到,确实没有证据表明支气管扩张剂对绝大多数患者有任何作用,我们和我们的家人认为它们有帮助只是这样。这份报纸是本月的编辑之选。那么,说到有用性的认知,谁接受了结核病新测试——干扰素γ释放试验(IGRA)测试的销售说辞呢?我承认我确实这么做了,受到来自许多方面的热情的鼓舞。遗憾的是,它们是一种复杂而昂贵的表达方式,与曼图图几乎完全相同——具有大致相同的特异性和敏感性。当然,我在这里强调的是Mantoux相对于IGRA的优点,Pollock、Roy和Kampmann在他们关于IGRA的文章《解释》(interpretation)中提供了一个有用的比较表。在杂志的其他地方,我们有一篇Jong和他的同事们关于如何使用新生儿TORCH测试的解释论文(见第93页),这是一个被滥用的泛化,而不是真正为正确的适应症做正确的测试。我们也有一个伟大的添加到Lio的令人着迷的皮肤科收藏-我希望你注意到,我已经避免了更明显的双关语拔你的头发在这个测试关于脱发(见106页)。一如既往,我鼓励任何有兴趣为杂志撰稿的作者与我们取得联系。为了强调这一点,我建议阅读Greg Skinner关于如何在临床实践中写一篇解决问题的文章(见第82页)。格雷格在这些论文上的编辑工作做得很出色,如果你有一个想法——即使是一个奇怪的想法——他是你讨论的人。我们期待收到您的来信。
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Highlights from this issue
When I was a very new paediatric doctor I worked in a unit that routinely used steam to treat children who had croup. It was a fantastic treatment—you could tell that you were doing something seriously efficacious; you would open the cubicle door to review the child and walk into this thick humid atmosphere— you could almost hear the witches chanting ‘Double, double toil and trouble; Fire burn, and caldron bubble’ in the distance. There was just one problem. It was rubbish. This was roundly demonstrated when new smoke detector systems were installed which were triggered by the steam, so we had to stop using it; it made absolutely no difference to the children we were treating. The evidence that steam was a waste of time was well established even by this time—plus the risks of directly or indirectly teaching parents insanities like ‘boil a kettle in the corner of the child’s room’ were apparent. But it took a practical issue like fire alarms to make us change our practice. I recalled this experience when reading the paper from Carroll and Sinivas (see page 113). They describe the very familiar scenario of a 13-month-old child with recurrent wheeze; indeed they comment that they’ve seen dozens of such patients in the last 12 months. It made me think that if they’d only so few, then no wonder they’ve the time to write such an excellent review; sometimes it seems that my practice is wall to wall with such patients. We’ve got used to using our slightly more modern ‘toil and trouble’ treatments —because, boy, nebulisers are jolly efficacious looking treatments, aren’t they? Indeed, if you compared a nebuliser with, say, a bone marrow transplant—perhaps the single most anticlimactic looking therapy I’ve ever observed—then I know which one looks the more efficacious. But in this careful review they note that there really is no evidence that bronchodilators are of any use in the vast majority of patients, and that our—and our families’—perception that they’re helpful is just that. This paper is this month’s Editor’s choice. So, speaking of perceptions of usefulness, who has bought into the sales pitch for the newer tests for TB—the interferon γ release assays (IGRA) tests? I’ll admit that I did, buoyed up by enthusiasm from a number of sources. A shame then that they’re a tricky and expensive way of saying pretty much exactly the same as a Mantoux—with roughly the same specificity and sensitivity. Of course, I’m stressing the positive points of a Mantoux over an IGRA here, and Pollock, Roy and Kampmann provide a useful comparison table between the two, in their Interpretations article on IGRA (see page 99). Elsewhere in the journal we have an Interpretations paper from Jong and colleagues (see page 93) on how to use neonatal TORCH testing—a much misused generalisation used instead of actually doing the right test for the right indication. We also have a great addition to Lio’s everfascinating Dermatophile collection —I hope you note that I’ve avoided the more obvious puns about pulling your hair out over this quiz on alopecias (see page 106). As ever I’d encourage any author of any background who has an interest in contributing to the journal to get in touch. By way of emphasising this, I’d suggest reading Greg Skinner’s article on How to write a Problem Solving in Clinical Practice paper (see page 82). Greg does an excellent editing job on these papers, and if you’ve got an idea for one— even a bizarre idea—he’s the person to discuss it with. We look forward to hearing from you.
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