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Archives of Disease in Childhood: Education & Practice Edition最新文献

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Placing education at the centre of the outpatient clinic improves learning and experiences for everyone using the multilevel attainment of learning, teaching and support (MALTS) approach 将教育放在门诊诊所的中心位置,利用多层次的学习、教学和支持(MALTS)方法,改善每个人的学习和体验
Pub Date : 2019-08-23 DOI: 10.1136/archdischild-2019-317544
M. Blair, E. Wortley, Kirsty McGuff
A large proportion of consultant time is spent in outpatient practice. This setting provides an excellent learning environment for different levels of a trainee if well organised. This article describes an evidence-based teaching approach and its evaluation by trainees, patients and carers in a typical district general hospital setting which it is hoped others might find helpful.
咨询医生的大部分时间花在门诊实践上。如果组织得当,这种环境为不同层次的学员提供了良好的学习环境。本文介绍了一种循证教学方法,并对典型的地区综合医院的学员、患者和护理人员进行了评估,希望能对其他人有所帮助。
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引用次数: 2
How to… collect urine samples from young children 如何收集幼儿的尿液样本
Pub Date : 2019-08-23 DOI: 10.1136/archdischild-2019-317237
J. Kaufman
Urine samples are commonly collected from young children to diagnose or exclude urinary tract infections, but collection from precontinent children is challenging. Each collection method has advantages and limitations. Non-invasive methods (urine pads, bags, clean catch) are convenient but can be time-consuming and are limited by sample contamination. Voiding stimulation methods (bladder-lumbar stimulation, Quick-Wee) can expedite clean catch collection. Invasive methods (catheter, suprapubic aspiration) can be more reliable, but require expertise to perform and cause pain for the child. This article reviews each collection method, and describes collection procedures, indications and strategies to optimise success and reduce contamination.
通常从幼儿身上采集尿样以诊断或排除尿路感染,但从失禁前儿童身上采集尿样具有挑战性。每种收集方法都有其优点和局限性。非侵入性方法(尿垫、尿袋、清洁袋)方便,但可能耗时,且受样本污染的限制。排尿刺激方法(膀胱-腰椎刺激,Quick-Wee)可以加速清洁收集。侵入性方法(导尿管、耻骨上抽吸)更可靠,但需要专业知识来操作,并给孩子带来疼痛。本文回顾了每种收集方法,并描述了收集程序,适应症和策略,以优化成功和减少污染。
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引用次数: 8
Newborn with hydrops fetalis and a severe supraventricular arrhythmia 新生儿伴有胎儿水肿和严重的室上性心律失常
Pub Date : 2019-08-21 DOI: 10.1136/archdischild-2019-317410
Elena Battistuz, L. Travan, J. Bua, A. Trappan, F. Galdo, M. Bobbo, E. Barbi, F. Risso
A 33+1-week female baby was born by caesarean section for worsening hydrops fetalis (HF) detected in the third trimester of pregnancy. Prenatal ultrasound showed a moderate enlargement of the right heart sections with a mild tricuspid insufficiency, without tachycardia, polyhydramnios, placentamegaly, renal agenesis and oesophageal atresia. At delivery, she developed transient hypotonia and apnoea and received nasal continuous positive airway pressure. Physical examination showed tachypnoea (70 breaths/min) and a moderate generalised subcutaneous oedema. Chest X-ray showed a cardiothoracic index of 0.82.At 90 min of life, her heart rate was 200–250 per minute. An ECG showed a paroxysmal supraventricular tachycardia (PSVT) with narrow complexes (figure 1). Vagal manoeuvres and five boluses of adenosine (250 μg/kg/dose) were ineffective, but she responded to amiodarone. Echocardiography showed severe tricuspid insufficiency and dilated right cardiac chambers. The baby presented further transient PSVT episodes, but these gradually improved on amiodarone, hydrochlorothiazide, spironolactone and furosemide. A primitive tricuspid valvulopathy with heart failure secondary to PSVT was diagnosed. …
一例33+1周的女婴因妊娠晚期发现的胎儿水肿(HF)加重而剖宫产。产前超声示右心切面中度增大,伴轻度三尖瓣功能不全,无心动过速、羊水过多、胎盘肥大、肾发育不全、食管闭锁。分娩时,她出现短暂性张力低下和呼吸暂停,并接受鼻腔持续气道正压通气。体格检查显示呼吸急促(70次/分)和中度全身皮下水肿。胸片示心胸指数0.82。生命90分钟时,她的心率为每分钟200-250次。心电图显示阵发性室上性心动过速(PSVT)伴狭窄复合体(图1)。迷走神经操纵和5大剂量腺苷(250 μg/kg/剂量)无效,但她对胺碘酮有反应。超声心动图显示严重的三尖瓣功能不全和右心室扩张。婴儿再次出现短暂性PSVT发作,但在胺碘酮、氢氯噻嗪、螺内酯和呋塞米治疗后逐渐改善。诊断为原发性三尖瓣病变伴继发于PSVT的心力衰竭。…
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引用次数: 2
A child in shock: carotid blowout syndrome 儿童休克:颈动脉爆裂综合征
Pub Date : 2019-08-10 DOI: 10.1136/archdischild-2019-317052
P. Stilwell, F. Robertson, S. Bhate, A. Sutcliffe
Paediatricians commonly encounter neck lumps during their routine clinical practice; vascular abnormalities, such as (pseudo)aneurysms, are a rare cause of these. Pseudoaneurysms of the carotid artery in children are usually the result of blunt or penetrating trauma, infection or vasculitis/connective tissue disorders. They can present with a variety of symptoms including neck pain, as a pulsatile neck mass or with compressive symptoms (for example, cranial nerve palsies or dyspnoea). Pseudoaneurysms carry a risk of rupture in which case they are fatal, unless immediate treatment is provided. We report a 17-month-old male child with idiopathic carotid artery blowout syndrome presenting with acute oropharyngeal haemorrhage leading to asystolic cardiac arrest. He was successfully resuscitated and emergency embolisation controlled the bleeding. Despite extensive left hemispheric infarct, he has survived. Carotid artery blowout syndrome needs to be recognised as a potential cause of major haemorrhage in childhood. The purpose of this case report is to remind readers of the differential diagnosis and work-up of a child presenting with a neck lump, to highlight important aspects of the acute management of major haemorrhage and massive blood transfusion in paediatrics, to describe the aetiology, presentation and management of carotid artery pseudoaneurysm in children and to discuss long term rehabilitation in patients with consequent neurological sequelae (including the need for input from multiple specialty teams).
儿科医生在日常临床实践中经常遇到颈部肿块;血管异常,如(假性)动脉瘤,是一个罕见的原因。儿童颈动脉假性动脉瘤通常是钝性或穿透性创伤、感染或血管炎/结缔组织疾病的结果。他们可以表现为多种症状,包括颈部疼痛、搏动性颈部肿块或压迫性症状(如脑神经麻痹或呼吸困难)。假性动脉瘤有破裂的危险,在这种情况下,除非立即治疗,否则是致命的。我们报告一个17个月大的男婴特发性颈动脉爆裂综合征,表现为急性口咽出血导致心脏停搏。他成功复苏,紧急栓塞控制了出血。尽管左半球大面积梗塞,他还是活了下来。颈动脉爆裂综合征需要被认为是儿童大出血的潜在原因。本病例报告的目的是提醒读者对儿童颈部肿块的鉴别诊断和检查,强调儿科大出血和大量输血的急性管理的重要方面,描述病因,儿童颈动脉假性动脉瘤的表现和治疗,并讨论随之而来的神经系统后遗症患者的长期康复(包括需要多个专业团队的投入)。
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引用次数: 0
Enteral lactoferrin supplementation did not reduce the risk of late-onset infection in very preterm infants 肠内乳铁蛋白补充并没有降低极早产儿迟发性感染的风险
Pub Date : 2019-08-10 DOI: 10.1136/archdischild-2019-317704
Rachel Toone, C. Harrison
Design: randomised clinical trial.1 Allocation: concealed (web-based randomisation).Blinding: parents, clinicians, investigators and outcome assessors were blinded.Setting : 37 neonatal units in the UK.Patients : infants born before 32 weeks gestation. Exclusion criteria were a severe congenital abnormality, an expected fast of over 14 days or no realistic chance of survival. A total of 2203 babies were enrolled for a target sample size of 2200.Intervention: placebo versus supplementing enteral feeds with 150 mg/kg/day of bovine lactoferrin once the infant was feeding over 12 mL/kg/day. This was continued until 34 weeks corrected gestation.Outcomes: the primary outcome was microbiologically confirmed or clinically suspected late-onset sepsis (LOS) (assessed locally initially, then by a central review committee) from trial entry to hospital discharge. Secondary outcomes were numerous but included necrotising enterocolitis (NEC), bronchopulmonary dysplasia (BPD), length of stay and mortality predischarge. Composite outcomes were also analysed.Follow-up period: …
设计:随机临床试验分配:隐蔽(基于网络的随机化)。盲法:对父母、临床医生、调查人员和结果评估人员进行盲法研究。环境:英国37个新生儿病房。患者:妊娠32周前出生的婴儿。排除标准是严重的先天性异常,预期快14天以上或没有实际的生存机会。总共有2203名婴儿被纳入,目标样本量为2200。干预:一旦婴儿喂养超过12ml /kg/天,安慰剂与补充150mg /kg/天的牛乳铁蛋白肠内饲料。这一过程一直持续到矫正妊娠34周。结果:主要结果是微生物学证实或临床怀疑的晚发性脓毒症(LOS)(最初由当地评估,然后由中央审查委员会评估)从试验开始到出院。次要结局有很多,但包括坏死性小肠结肠炎(NEC)、支气管肺发育不良(BPD)、住院时间和出院前死亡率。对综合结果也进行了分析。随访期:……
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引用次数: 1
Fifteen-minute consultation: Managing a child with a new-onset squint 15分钟咨询:处理一个新发斜视的孩子
Pub Date : 2019-08-02 DOI: 10.1136/archdischild-2019-317817
A. Hopkins, I. Simmons
Objective To provide a systematic approach to the child with a new squint. Method Review of the current available literature. Conclusion Squint is a common presentation in the paediatric population. Although the parents’ primary concern may be cosmetic, a new squint in childhood may be the first sign of a serious or life-threatening ocular or neurological pathology. Thorough assessment and timely referral are essential.
目的为儿童新斜视的治疗提供系统的方法。方法查阅现有文献。结论斜视在儿童中是一种常见的表现。虽然父母主要关心的可能是美观,但儿童时期新的斜视可能是严重或危及生命的眼部或神经病理学的第一个迹象。彻底的评估和及时的转诊至关重要。
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引用次数: 1
Drug-free inactive disease in juvenile idiopathic arthritis can be achieved for 40% of patients 青少年特发性关节炎的无药无活动性疾病可达到40%的患者
Pub Date : 2019-07-31 DOI: 10.1136/archdischild-2019-317833
L. Chapman, A. Friend
Study design : randomised, single-blind trial.Setting: The Netherlands.1 Patients: 94 patients with new-onset (symptom duration <18 months) juvenile idiopathic arthritis (JIA) who had not been exposed to previous disease-modifying antirheumatic drug (DMARD) therapy.Interventions: conventional systemic DMARD monotherapy (methotrexate (MTX) or sulfasalazine) versus MTX plus 6-week tapered course of prednisolone vs MTX plus etarnercept.Outcomes: time to inactive disease; time to flare after the first episode of drug-free inactive disease (DFID).Main results: …
研究设计:随机、单盲试验。患者:94例新发(症状持续时间<18个月)青少年特发性关节炎(JIA)患者,既往未接受过改善疾病的抗风湿药物(DMARD)治疗。干预措施:常规系统性DMARD单药治疗(甲氨蝶呤(MTX)或柳氮磺胺嘧啶)vs甲氨蝶呤加6周逐渐减少的泼尼松龙vs甲氨蝶呤加依他那西普。结局:到非活动疾病的时间;无药非活动性疾病(DFID)首次发作后的发作时间。主要结果:…
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引用次数: 0
Highlights from this issue 本期重点报道
Pub Date : 2019-07-19 DOI: 10.1136/archdischild-2019-317811
I. Wacogne
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引用次数: 0
Highlights from this issue 本期重点报道
Pub Date : 2019-04-29 DOI: 10.1136/archdischild-2019-317483
I. Wacogne
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引用次数: 0
Highlights from this issue 本期重点报道
Pub Date : 2019-03-20 DOI: 10.1136/archdischild-2019-317138
I. Wacogne
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期刊
Archives of Disease in Childhood: Education & Practice Edition
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