衰老对兔眼生物力学特性的影响

Xiaojun Wang, Weiyi Chen, Chunsheng Liu, Yanjun Li, Lei Ma
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引用次数: 3

摘要

为了研究老化对眼力学性能的影响,将20只健康眼兔分为幼年(3个月)、青年(5个月)、中年(18个月)和老年(48个月)4组。通过测量角膜中央厚度(CCT)和眼压(IOP),测定4个不同年龄组的眼体积随眼压的变化情况。然后制备巩膜条,利用Instron 5544试验机进行单轴拉伸生物力学性能测量。结果显示:4组患儿在30分钟内巩膜蠕变速率的CCT均低于老年(p < 0.05)。
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Effects of Aging on Biomechanics Properties in Rabbit Eyes
In order to study the effects of aging on biomechanics properties, twenty rabbits with healthy eyes were divided into four groups including infancy (3 months), youth (5 months), midlife (18 months) and agedness (48 months). After measuring the central corneal thickness (CCT) and the intraocular pressure (IOP), the alteration of eye volume with intraocular pressure was determined of four different age groups. Then sclera strips were prepared for biomechanical properties measurement through uniaxial tension using an Instron 5544 test machine. Our results showed: The CCT of the infancy was lower than the agedness (p 0.05) in four groups for the creep rate of sclera in 30 minutes.
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